Drug therapy for osteoporosis in older adults

IR Reid, EO Billington - The Lancet, 2022 - thelancet.com
The goal of osteoporosis management is to prevent fractures. Several pharmacological
agents are available to lower fracture risk, either by reducing bone resorption or by …

[HTML][HTML] UK clinical guideline for the prevention and treatment of osteoporosis

CL Gregson, DJ Armstrong, J Bowden, C Cooper… - Archives of …, 2022 - Springer
Abstract Summary The National Osteoporosis Guideline Group (NOGG) has revised the UK
guideline for the assessment and management of osteoporosis and the prevention of …

[HTML][HTML] The clinician's guide to prevention and treatment of osteoporosis

MS LeBoff, SL Greenspan, KL Insogna… - Osteoporosis …, 2022 - Springer
Osteoporosis is the most common metabolic bone disease in the USA and the world. It is a
subclinical condition until complicated by fracture (s). These fractures place an enormous …

Bone fragility in diabetes: novel concepts and clinical implications

LC Hofbauer, B Busse, R Eastell, S Ferrari… - The Lancet Diabetes & …, 2022 - thelancet.com
Increased fracture risk represents an emerging and severe complication of diabetes. The
resulting prolonged immobility and hospitalisations can lead to substantial morbidity and …

Postmenopausal osteoporosis

MD Walker, E Shane - New England Journal of Medicine, 2023 - Mass Medical Soc
Key Clinical Points Postmenopausal Osteoporosis Fragility fractures are very common
among postmenopausal women and are associated with increased morbidity, mortality, and …

Pharmacologic treatment of primary osteoporosis or low bone mass to prevent fractures in adults: a living clinical guideline from the American College of Physicians

A Qaseem, LA Hicks… - Annals of internal …, 2023 - acpjournals.org
An update is available for this article. Description: This guideline updates the 2017 American
College of Physicians (ACP) recommendations on pharmacologic treatment of primary …

Effectiveness and safety of treatments to prevent fractures in people with low bone mass or primary osteoporosis: a living systematic review and network meta-analysis …

C Ayers, D Kansagara, B Lazur, R Fu… - Annals of internal …, 2023 - acpjournals.org
An update is available for this article. Background: The prevalence of osteoporosis is
increasing in the United States. Purpose: To evaluate low bone mass and osteoporosis …

Fracture risk and management of discontinuation of denosumab therapy: a systematic review and position statement by ECTS

E Tsourdi, MC Zillikens, C Meier, JJ Body… - The Journal of …, 2021 - academic.oup.com
Context Denosumab discontinuation is characterized by an increase in bone turnover
overriding pretreatment status, a rapid bone loss in the majority and multiple vertebral …

[HTML][HTML] Targeting signaling pathways in prostate cancer: mechanisms and clinical trials

Y He, W Xu, YT Xiao, H Huang, D Gu… - Signal transduction and …, 2022 - nature.com
Prostate cancer (PCa) affects millions of men globally. Due to advances in understanding
genomic landscapes and biological functions, the treatment of PCa continues to improve …

Osteoporosis treatment: recent developments and ongoing challenges

S Khosla, LC Hofbauer - The lancet Diabetes & endocrinology, 2017 - thelancet.com
Osteoporosis is an enormous and growing public health problem. Once considered an
inevitable consequence of ageing, it is now eminently preventable and treatable. Ironically …