Cell death plays important roles in living organisms and is a hallmark of numerous disorders
such as cardiovascular diseases, sepsis and acute pancreatitis. Moreover, cell death also …

Fungal aromatic polyketides display a very diverse and widespread group of natural
products. Due to their excellent light absorption properties and widely studied biological …

Necrosis-avid agents possess exploitable theragnostic utilities including evaluation of tissue
viability, monitoring of therapeutic efficacy as well as diagnosis and treatment of necrosis …

Metal–organic complexes (MOCs) are emerging developing functional materials, the
different categories of metal ions and organic biomolecules provide great possibilities for the …

Simple Summary Hypoxic conditions are common in solid tumors and are very often
connected with the poor prognosis of cancer patients. The lack of oxygen often causes the …

The purpose of this study is to develop a specific CXCR4-targeting radioiodinated agent
(125I-or 131I-pentixather) for single-photon-emission-computed-tomography (SPECT) …

Necrotic myocardium imaging can provide great indicators of salvaged myocardial areas for
clinical guidances to patients with myocardial infarction (MI). One of the key challenges in …

Abstract Background Iodine-131 labeled hypericin (131 I-Hyp) has been utilized as a
necrosis-avid theragnostic tracer in a dual targeting pan-anticancer strategy called …

Necrosis is an important biomarker, which only occurs in pathological situations. Tracking of
necrosis avid agents is of crucial importance toward understanding their mechanisms …

Tracking of necrosis avid agents is of crucial importance toward understanding their
mechanisms. We explored the cellular localisation of rhein by synthesising a clickable …