From Cannabis sativa to Cannabidiol: Promising Therapeutic Candidate for the Treatment of Neurodegenerative Diseases
Cannabis sativa, commonly known as marijuana, contains a pool of secondary plant
metabolites with therapeutic effects. Besides Δ9-tetrahydrocannabinol that is the principal …
metabolites with therapeutic effects. Besides Δ9-tetrahydrocannabinol that is the principal …
Mitochondrial Modulators: the defender
Mitochondria are widely considered the “power hub” of the cell because of their pivotal roles
in energy metabolism and oxidative phosphorylation. However, beyond the production of …
in energy metabolism and oxidative phosphorylation. However, beyond the production of …
Loliolide, a new therapeutic option for neurological diseases? In vitro neuroprotective and anti-inflammatory activities of a monoterpenoid lactone isolated from codium …
Parkinsons Disease (PD) is the second most common neurodegenerative disease
worldwide, and is characterized by a progressive degeneration of dopaminergic neurons …
worldwide, and is characterized by a progressive degeneration of dopaminergic neurons …
Antioxidant and Neuroprotective Potential of the Brown Seaweed Bifurcaria bifurcata in an in vitro Parkinson's Disease Model
Bifurcaria bifurcata is a marine brown seaweed mainly found on the Atlantic coast. Herein,
we report the antioxidant and neuroprotective activities of seven fractions (F1–F7) obtained …
we report the antioxidant and neuroprotective activities of seven fractions (F1–F7) obtained …
Marine-derived components: can they be a potential therapeutic approach to Parkinson's disease?
J Silva, C Alves, F Soledade, A Martins, S Pinteus… - Marine drugs, 2023 - mdpi.com
The increase in the life expectancy average has led to a growing elderly population, thus
leading to a prevalence of neurodegenerative disorders, such as Parkinson's disease (PD) …
leading to a prevalence of neurodegenerative disorders, such as Parkinson's disease (PD) …
α-Cyperone Attenuates H2O2-Induced Oxidative Stress and Apoptosis in SH-SY5Y Cells via Activation of Nrf2
B Huang, J Liu, S Fu, Y Zhang, Y Li, D He… - Frontiers in …, 2020 - frontiersin.org
α-Cyperone, extracted from Cyperus rotundus, has been reported to inhibit microglia-
mediated neuroinflammation. Oxidative stress and apoptosis play crucial roles in the course …
mediated neuroinflammation. Oxidative stress and apoptosis play crucial roles in the course …
[HTML][HTML] Single and combined effects of regulated and emerging mycotoxins on viability and mitochondrial function of SH-SY5Y cells
N Pérez-Fuentes, R Alvariño, A Alfonso… - Food and Chemical …, 2021 - Elsevier
Co-occurrence of emerging and regulated mycotoxins in contaminated samples has been
widely documented, but studies about their combined toxicity are scarce. In this report, the …
widely documented, but studies about their combined toxicity are scarce. In this report, the …
Disclosing the potential of eleganolone for Parkinson's disease therapeutics: Neuroprotective and anti-inflammatory activities
The treatment of Parkinson´ s disease (PD) has benefited from significant advances
resulting from the increasing research efforts focused on new therapeutics. However, the …
resulting from the increasing research efforts focused on new therapeutics. However, the …
[HTML][HTML] Eclalbasaponin I from Aralia elata (Miq.) Seem. reduces oxidative stress-induced neural cell death by autophagy activation
W Wang, GD Yao, XY Shang, JC Gao, Y Zhang… - Biomedicine & …, 2018 - Elsevier
Oxidative stress has been proposed to contribute to DNA damage and is involved in many
neurodegenerative diseases. It has been reported that Aralia elata (Miq.) Seem.(A. elata) …
neurodegenerative diseases. It has been reported that Aralia elata (Miq.) Seem.(A. elata) …
[HTML][HTML] Neuroprotective effects of fluorophore-labelled manganese complexes: Determination of ROS production, mitochondrial membrane potential and confocal …
In this work, four manganese (II) complexes derived from the ligands H 2 L 1-H 2 L 4, that
incorporate dansyl or tosyl fluorescent dyes, have been investigated in term of their …
incorporate dansyl or tosyl fluorescent dyes, have been investigated in term of their …