[HTML][HTML] Nutritional immunity: the battle for nutrient metals at the host–pathogen interface

CC Murdoch, EP Skaar - Nature Reviews Microbiology, 2022 - nature.com
Trace metals are essential micronutrients required for survival across all kingdoms of life.
From bacteria to animals, metals have critical roles as both structural and catalytic cofactors …

[HTML][HTML] Zinc in plants: Integrating homeostasis and biofortification

C Stanton, D Sanders, U Krämer, D Podar - Molecular Plant, 2022 - cell.com
Zinc plays many essential roles in life. As a strong Lewis acid that lacks redox activity under
environmental and cellular conditions, the Zn 2+ cation is central in determining protein …

Metallo-β-lactamases in the age of multidrug resistance: from structure and mechanism to evolution, dissemination, and inhibitor design

G Bahr, LJ Gonzalez, AJ Vila - Chemical reviews, 2021 - ACS Publications
Antimicrobial resistance is one of the major problems in current practical medicine. The
spread of genes coding for resistance determinants among bacteria challenges the use of …

An overlooked and underrated endemic mycosis—Talaromycosis and the pathogenic fungus Talaromyces marneffei

F Wang, RH Han, S Chen - Clinical Microbiology Reviews, 2023 - Am Soc Microbiol
Talaromycosis is an invasive mycosis endemic in tropical and subtropical Asia and is
caused by the pathogenic fungus Talaromyces marneffei. Approximately 17,300 cases of T …

[HTML][HTML] Zinc in human health and infectious diseases

M Maywald, L Rink - Biomolecules, 2022 - mdpi.com
During the last few decades, the micronutrient zinc has proven to be an important metal ion
for a well-functioning immune system, and thus also for a suitable immune defense …

[HTML][HTML] Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut

J Behnsen, H Zhi, AT Aron, V Subramanian… - Nature …, 2021 - nature.com
Zinc is an essential cofactor for bacterial metabolism, and many Enterobacteriaceae express
the zinc transporters ZnuABC and ZupT to acquire this metal in the host. However, the …

[HTML][HTML] Influence of maternal milk on the neonatal intestinal microbiome

KP Gopalakrishna, TW Hand - Nutrients, 2020 - mdpi.com
The intestinal microbiome plays an important role in maintaining health throughout life. The
microbiota develops progressively after birth and is influenced by many factors, including the …

[HTML][HTML] Protein metalation in biology

AW Foster, TR Young, PT Chivers… - Current Opinion in …, 2022 - Elsevier
Inorganic metals supplement the chemical repertoire of organic molecules, especially
proteins. This requires the correct metals to associate with proteins at metalation. Protein …

Obesity and dysregulated innate immune responses: impact of micronutrient deficiencies

F Vrieling, R Stienstra - Trends in Immunology, 2023 - cell.com
Obesity is associated with the development of various complications, including diabetes,
atherosclerosis, and an increased risk for infections, driven by dysfunctional innate immune …

[HTML][HTML] Zinc deficiency—An independent risk factor in the pathogenesis of haemorrhagic stroke?

K Grüngreiff, T Gottstein, D Reinhold - Nutrients, 2020 - mdpi.com
Zinc is an essential trace element for human health and plays a fundamental role in
metabolic, immunological and many other biological processes. The effects of zinc are …