The ambiguous role of sirtuins in head and neck squamous cell carcinoma

D Ezhilarasan, T Lakshmi, M Subha… - Oral …, 2022 - Wiley Online Library
Oral cancer is one of the most leading cancer responsible for significant morbidity and
mortality. The sirtuins (SIRTs) are a family of class III histone deacetylases and are known to …

Salivary gland function, development, and regeneration

AM Chibly, MH Aure, VN Patel… - Physiological …, 2022 - journals.physiology.org
Salivary glands produce and secrete saliva, which is essential for maintaining oral health
and overall health. Understanding both the unique structure and physiological function of …

[HTML][HTML] Radiation-induced salivary gland dysfunction: mechanisms, therapeutics and future directions

KJ Jasmer, KE Gilman, K Muñoz Forti… - Journal of clinical …, 2020 - mdpi.com
Salivary glands sustain collateral damage following radiotherapy (RT) to treat cancers of the
head and neck, leading to complications, including mucositis, xerostomia and …

Mitigating acute chemotherapy-associated adverse events in patients with cancer

NM Kuderer, A Desai, MB Lustberg… - Nature Reviews Clinical …, 2022 - nature.com
Despite the enthusiasm surrounding novel targeted agents and immunotherapies,
chemotherapy remains the mainstay treatment for most human malignancies, either alone or …

Use of amifostine for cytoprotection during radiation therapy: a review

M King, S Joseph, A Albert, TV Thomas, MR Nittala… - Oncology, 2020 - karger.com
Background: Radiation therapy is a cornerstone of the therapeutic modalities used in
modern oncology. However, it is sometimes limited in its ability to achieve optimal tumor …

Oral mucositis in head and neck cancer: Evidence-based management and review of clinical trial data

A Blakaj, M Bonomi, ME Gamez, DM Blakaj - Oral oncology, 2019 - Elsevier
Oral Mucositis (OM) continues to be an oncologic challenge in the context of antineoplastic
therapy for head and neck cancer (HNC) treatment. It is a dose-limiting toxicity of …

Photobiomodulation and cancer: what is the truth?

MR Hamblin, ST Nelson, JR Strahan - Photomedicine and laser …, 2018 - liebertpub.com
Background: Photobiomodulation (PBM) therapy is a rapidly growing approach to stimulate
healing, reduce pain, increase athletic performance, and improve general wellness …

[HTML][HTML] Status of treatment and prophylaxis for radiation-induced oral mucositis in patients with head and neck cancer

S Liu, Q Zhao, Z Zheng, Z Liu, L Meng, L Dong… - Frontiers in …, 2021 - frontiersin.org
Radiation-induced oral mucositis (RIOM) is one of the most frequent complications in head
and neck cancer (HNC) patients undergoing radiotherapy (RT). It is a type of mucosal injury …

Tumor safety and side effects of photobiomodulation therapy used for prevention and management of cancer treatment toxicities. A systematic review

M de Pauli Paglioni, ALD Araújo, LPA Arboleda… - Oral Oncology, 2019 - Elsevier
Photobiomodulation therapy (PBMT), also known as low-level laser therapy (LLLT), has
been increasingly used for the treatment of toxicities related to cancer treatment. One of the …

Early side effects of radiation treatment for head and neck cancer

I Brook - Cancer/radiotherapie, 2021 - Elsevier
Purpose of this review of medical literature is to present the immediate side effects of
radiation therapy for head and neck cancer and their treatment. The likelihood and severity …