Pancreatic stellate cells (PaSCs) are myofibroblast-like cells found in the areas of the
pancreas that have exocrine function. PaSCs are regulated by autocrine and paracrine …

Chronic pancreatitis (CP) is characterized by progressive pancreatic damage that eventually
results in significant impairment of exocrine as well as endocrine functions of the gland. In …

Background: There are no established guidelines for pathologic diagnosis/reporting of
intraductal papillary mucinous neoplasms (IPMNs). Design: An international …

This paper gives practical guidelines for diagnosis and treatment of chronic pancreatitis.
Statements have been elaborated by working teams of experts, by searching for and …

OBJECTIVES: Pancreatic-enzyme replacement therapy (PERT) is the standard of care to
prevent maldigestion, malnutrition, and excessive weight loss in patients with exocrine …

Background The clinical course of chronic pancreatitis is still unpredictable, which relates to
the lack of the availability of a clinical classification. Therefore, patient populations cannot be …

Objectives: Pancreatic resection for cancer may produce pancreatic exocrine insufficiency
(PEI), which is poorly understood. This study examined the coefficient of fat absorption …

Aliment Pharmacol Ther 2011; 33: 1152–1161 Summary Background Pancreatic enzyme
replacement therapy (PERT) is necessary to prevent severe maldigestion and unwanted …

A workshop sponsored by the National Institute of Diabetes and Digestive and Kidney
Diseases focused on research gaps and opportunities in total pancreatectomy with islet …

Restitution of normal fat absorption in exocrine pancreatic insufficiency remains an elusive
goal. Although many patients achieve satisfactory clinical results with enzyme therapy, few …