Inflammatory bowel disease (IBD), as a global disease, has attracted much research
interest. Constant research has led to a better understanding of the disease condition and …

Crohn disease is a chronic idiopathic inflammatory bowel disease condition characterized
by skip lesions and transmural inflammation that can affect the entire gastrointestinal tract …

Inflammation and its resolution is under-studied in medicine despite being essential for
understanding the development of chronic inflammatory disease. In this review article, we …

Objectives We sought to evaluate the association between obesity and response to anti-
tumor necrosis factor-α (TNF) agents, through a systematic review and meta-analysis …

Abstract Background Immune checkpoint inhibitors (ICIs) have improved cancer outcomes.
However, immune-related adverse effects are common. The aim was to investigate the …

Ulcerative colitis is a chronic idiopathic inflammatory bowel disease characterized by
continuous mucosal inflammation that starts in the rectum and extends proximally. Typical …

Background There are limited data to inform positioning of agents for treating moderate‐
severe Crohn's disease (CD). Aim We assessed comparative efficacy and safety of first‐line …

Abstract Background and Aims We sought to analyze whether response to a second-line
biologic varies depending on the reason for discontinuation of the primary anti-TNF agent …

Background & Aims Biologics are used routinely in pregnant women with inflammatory
bowel disease (IBD), but large-scale data reporting adverse pregnancy outcomes among …

Background Allergic rhinitis (AR) is characterized by mucosal inflammation, driven by
activated immune cells. Mast cells and TH 2 cells might decrease epithelial barrier integrity …