Stimuli-responsive therapeutic metallodrugs

X Wang, X Wang, S Jin, N Muhammad, Z Guo - Chemical reviews, 2018 - ACS Publications
The success of platinum-based anticancer agents has motivated the exploration of novel
metal-based drugs for several decades, whereas problems such as drug-resistance and …

The development of anticancer ruthenium (II) complexes: from single molecule compounds to nanomaterials

L Zeng, P Gupta, Y Chen, E Wang, L Ji… - Chemical Society …, 2017 - pubs.rsc.org
Cancer is rapidly becoming the top killer in the world. Most of the FDA approved anticancer
drugs are organic molecules, while metallodrugs are very scarce. The advent of the first …

MOF materials as therapeutic agents, drug carriers, imaging agents and biosensors in cancer biomedicine: Recent advances and perspectives

A Bieniek, AP Terzyk, M Wiśniewski, K Roszek… - Progress in Materials …, 2021 - Elsevier
We summarize recent advances in application of MOFs as therapeutic agents, drug carriers,
imaging agents and biosensors in cancer biomedicine. A holistic perspective is adopted to …

Health beneficial and pharmacological properties of p-cymene

A Balahbib, N El Omari, NEL Hachlafi, F Lakhdar… - Food and Chemical …, 2021 - Elsevier
Abstract p-cymene also known as p-cymol or p-isopropyltoluene is an alkyl-substituted
aromatic compound naturally occurring in essential oils (EOs) of various aromatic plants …

[HTML][HTML] Advances in the design of organometallic anticancer complexes

P Zhang, PJ Sadler - Journal of Organometallic Chemistry, 2017 - Elsevier
Organometallic complexes containing ligands such as CO, carbenes, alkyls, phenyls, π-
bound alkynes, alkenes, cyclopentadienyls and arenes possess properties which have often …

Combination of Ru (II) complexes and light: new frontiers in cancer therapy

C Mari, V Pierroz, S Ferrari, G Gasser - Chemical science, 2015 - pubs.rsc.org
The synergistic action of light, oxygen and a photosensitizer (PS) has found applications for
decades in medicine under the name of photodynamic therapy (PDT) for the treatment of …

The development of RAPTA compounds for the treatment of tumors

BS Murray, MV Babak, CG Hartinger… - Coordination Chemistry …, 2016 - Elsevier
Abstract Ruthenium (II)-arene RAPTA-type compounds have been extensively explored for
their medicinal properties. Herein a comprehensive review of this class of compounds is …

Advancement of metal compounds as therapeutic and diagnostic metallodrugs: Current frontiers and future perspectives

I Yousuf, M Bashir, F Arjmand, S Tabassum - Coordination Chemistry …, 2021 - Elsevier
Coordination compounds on account of distinctive features of metal ions that include
variable oxidation states, diverse range of geometries and coordination numbers …

Colorectal cancer chemotherapy: the evolution of treatment and new approaches

RM McQuade, V Stojanovska… - Current medicinal …, 2017 - ingentaconnect.com
Colorectal cancer (CRC) is one the greatest contributors to cancer related mortality.
Although 5 year survival rate for patients at the early stage of CRC (stages I and II) is above …

Metal-based drugs that break the rules

CS Allardyce, PJ Dyson - Dalton transactions, 2016 - pubs.rsc.org
Cisplatin and other platinum compounds have had a huge impact in the treatment of cancers
and are applied in the majority of anticancer chemotherapeutic regimens. The success of …