Endothelial and vascular smooth muscle dysfunction in hypertension
The development of essential hypertension involves several factors. Vascular dysfunction,
characterized by endothelial dysfunction, low-grade inflammation and structural remodeling …
characterized by endothelial dysfunction, low-grade inflammation and structural remodeling …
[HTML][HTML] Comparison of solid-phase extraction methods for efficient purification of phosphopeptides with low sample amounts
Efficient phosphoproteomic analysis of small amounts of biological samples (eg tissue
biopsies) requires carefully selected enrichment and purification steps prior to the nanoflow …
biopsies) requires carefully selected enrichment and purification steps prior to the nanoflow …
The beneficial health effects of puerarin in the treatment of cardiovascular diseases: from mechanisms to therapeutics
Q Wan, Q Lu, S Luo, C Guan, H Zhang - Naunyn-Schmiedeberg's Archives …, 2024 - Springer
Cardiovascular diseases (CVDs) are the leading causes of death globally that seriously
threaten human health. Although novel western medicines have continued to be discovered …
threaten human health. Although novel western medicines have continued to be discovered …
From Living in Saltwater to a Scarcity of Salt and Water, and Then an Overabundance of Salt—The Biological Roller Coaster to Which the Renin–Angiotensin System …
GL Nádasy, A Balla, M Szekeres - Biomedicines, 2023 - mdpi.com
Angiotensin II (Ang II) is a hormone with much more complex actions than is typical for other
agonists with heterotrimeric G protein-coupled receptors (GPCRs). Its principal receptor …
agonists with heterotrimeric G protein-coupled receptors (GPCRs). Its principal receptor …
An unexpected enzyme in vascular smooth muscle cells: angiotensin II upregulates cholesterol-25-hydroxylase gene expression
Angiotensin II (AngII) is a vasoactive peptide hormone, which, under pathological conditions,
contributes to the development of cardiovascular diseases. Oxysterols, including 25 …
contributes to the development of cardiovascular diseases. Oxysterols, including 25 …
[HTML][HTML] Enhanced cerebral hemodynamics and cognitive function via knockout of dual-specificity protein phosphatase 5
Alzheimer's Disease (AD) and Alzheimer's Disease-Related Dementias (ADRD) are
neurodegenerative disorders. Recent studies suggest that cerebral hypoperfusion is an …
neurodegenerative disorders. Recent studies suggest that cerebral hypoperfusion is an …
Transcriptome analysis of mRNAs, lncRNAs, and miRNAs in the skeletal muscle of Tibetan chickens at different developmental stages
J Li, C Chen, R Zhao, J Wu, Z Li - Frontiers in Physiology, 2023 - frontiersin.org
Introduction: As a valuable genetic resource, native birds can contribute to the sustainable
development of animal production. Tibetan chickens, known for their special flavor, are one …
development of animal production. Tibetan chickens, known for their special flavor, are one …
Uncovering the mechanism of Naoxintong capsule against hypertension based on network analysis and in vitro experiments
X Chen, L Hu, R Wang, M Luo, C Wei… - Chemical Biology & …, 2024 - Wiley Online Library
Naoxintong capsule (NXT) is a clinical drug for the treatment of cardiovascular diseases, but
its pharmacological mechanism against hypertension remains unclear. Data concerning the …
its pharmacological mechanism against hypertension remains unclear. Data concerning the …
[PDF][PDF] Investigation of two clinically important G protein-coupled receptors: V2 vasopressin receptor and AT1 angiotensin receptor
L Szalai - 2023 - repo.lib.semmelweis.hu
G protein-coupled receptors (GPCRs) are key cell-surface proteins which constitute the
largest class of receptor and membrane proteins in the human proteome. They transduce …
largest class of receptor and membrane proteins in the human proteome. They transduce …