Role of prostaglandin E2 in macrophage polarization: Insights into atherosclerosis
W Wang, M Liang, L Wang, W Bei, X Rong, J Xu… - Biochemical …, 2023 - Elsevier
Atherosclerosis, a trigger of cardiovascular disease, poses grave threats to human health.
Although atherosclerosis depends on lipid accumulation and vascular wall inflammation …
Although atherosclerosis depends on lipid accumulation and vascular wall inflammation …
The relevance of pathophysiological alterations in redox signaling of 4-hydroxynonenal for pharmacological therapies of major stress-associated diseases
M Jaganjac, L Milkovic, A Gegotek, M Cindric… - Free Radical Biology …, 2020 - Elsevier
Modern analytical methods combined with the modern concepts of redox signaling revealed
4-hydroxy-2-nonenal (4-HNE) as particular growth regulating factor involved in redox …
4-hydroxy-2-nonenal (4-HNE) as particular growth regulating factor involved in redox …
Inhibitors of NLRP3 inflammasome in ischemic heart disease: focus on functional and redox aspects
P Pagliaro, C Penna - Antioxidants, 2023 - mdpi.com
Myocardial ischemia-reperfusion injury (MIRI) is caused by several mechanisms, including
the production of reactive oxygen species (ROS), altered cellular osmolarity, and …
the production of reactive oxygen species (ROS), altered cellular osmolarity, and …
When nitrosative stress hits the endoplasmic reticulum: Possible implications in oxLDL/oxysterols-induced endothelial dysfunction
Oxidized LDL (oxLDL) and oxysterols are known to play a crucial role in endothelial
dysfunction (ED) by inducing endoplasmic reticulum stress (ERS), inflammation, and …
dysfunction (ED) by inducing endoplasmic reticulum stress (ERS), inflammation, and …
The emerging role of COX-2, 15-LOX and PPARγ in metabolic diseases and cancer: an introduction to novel multi-target directed ligands (MTDLs)
Emerging evidence supports an intertwining framework for the involvement of different
inflammatory pathways in a common pathological background for a number of disorders. Of …
inflammatory pathways in a common pathological background for a number of disorders. Of …
Different approaches in therapy aiming to stabilize an unstable atherosclerotic plaque
M Kowara, A Cudnoch-Jedrzejewska - International Journal of Molecular …, 2021 - mdpi.com
Atherosclerotic plaque vulnerability is a vital clinical problem as vulnerable plaques tend to
rupture, which results in atherosclerosis complications—myocardial infarctions and …
rupture, which results in atherosclerosis complications—myocardial infarctions and …
Proeryptotic activity of 4-hydroxynonenal: A new potential physiopathological role for lipid peroxidation products
Background: Eryptosis is a physiological, apoptosis-like death of injured erythrocytes crucial
to prevent premature haemolysis and the pathological sequalae generated by cell-free …
to prevent premature haemolysis and the pathological sequalae generated by cell-free …
Up-regulation of PCSK6 by lipid oxidation products: A possible role in atherosclerosis
G Testa, E Staurenghi, S Giannelli, B Sottero… - Biochimie, 2021 - Elsevier
Atherosclerosis is a degenerative disease characterized by lesions that develop in the wall
of large-and medium-sized arteries due to the accumulation of low-density lipoproteins …
of large-and medium-sized arteries due to the accumulation of low-density lipoproteins …
Induction of cyclooxygenase-2 by overexpression of the human NADPH oxidase 5 (NOX5) gene in aortic endothelial cells
J Marqués, A Cortés, Á Pejenaute, E Ansorena… - Cells, 2020 - mdpi.com
Oxidative stress is a main molecular mechanism that underlies cardiovascular diseases. A
close relationship between reactive oxygen species (ROS) derived from NADPH oxidase …
close relationship between reactive oxygen species (ROS) derived from NADPH oxidase …
27‐hydroxycholesterol promotes oligodendrocyte maturation: implications for hypercholesterolemia‐associated brain white matter changes
V Alanko, A Gaminde‐Blasco, T Quintela‐López… - Glia, 2023 - Wiley Online Library
Abstract Oxidized cholesterol metabolite 27‐hydroxycholesterol (27‐OH) is a potential link
between hypercholesterolemia and neurodegenerative diseases since unlike peripheral …
between hypercholesterolemia and neurodegenerative diseases since unlike peripheral …