Capsaicin, the active ingredient in hot chilli peppers, has selective actions on unmyelinated
C-fibres and thinly myelinated A primary sensory neurones [37, 100](Table 1). Most …

Definition of the physiological and pharmacological properties of primary afferent neurons
by the use of capsaicin and its analogues (eg resiniferatoxin) has represented one of the …

Capsaicin activates a non-specific cation conductance in mammalian sensory neurones. If
capsaicin is applied continuously or repeatedly then there is a progressive decline in …

Antibiotics halt the growth of bacteria by targeting core, essential physiology that is required
for life on standard microbiological media. Many more biochemical and virulence processes …

Abstract Na+‐K+‐2Cl− co‐transporter (NKCC 1) plays an important role in traumatic brain
injury (TBI)‐induced brain edema via the MAPK cascade. The transient receptor potential …

Intraplantar injection of capsaicin (1.6 μg/paw) into the mouse hindpaw produced an acute
paw-licking/biting response. This study was designed (1) to investigate the antinociceptive …

▪ Abstract Chemical activation of sensory neurons plays an important role in the
somatosensory system. The actions of both endogenous mediators such as excitatory amino …

Transient receptor potential channels (TRPs) regulate tumor growth via calcium-dependent
mechanisms. The (thermosensitive) capsaicin receptor TRPV1 is overexpressed in …

Nerve terminals of primary sensory neurons are influenced by their environment through
target derived trophic factors, like nerve growth factor (NGF) or glial cell line-derived …

1 Cigarette smoke increases vascular permeability in rat airways by activating release of
tachykinin from capsaicin‐sensitive sensory nerves. However, the mechanism by which …