Pathophysiology of acute respiratory distress syndrome and COVID-19 lung injury

KE Swenson, ER Swenson - Critical care clinics, 2021 - criticalcare.theclinics.com
Acute respiratory distress syndrome (ARDS) is a complex syndrome of acute lung injury
leading to noncardiogenic pulmonary edema from many causes that is heterogenous in its …

Ventilator-induced lung injury

JR Beitler, A Malhotra… - Clinics in chest …, 2016 - chestmed.theclinics.com
As with most medical and pharmacologic interventions, mechanical ventilation must be
titrated within a therapeutic window, providing the required lifesustaining support while …

The" baby lung" became an adult

L Gattinoni, JJ Marini, A Pesenti, M Quintel… - Intensive care …, 2016 - Springer
The baby lung was originally defined as the fraction of lung parenchyma that, in acute
respiratory distress syndrome (ARDS), still maintains normal inflation. Its size obviously …

Effect of mechanical power on intensive care mortality in ARDS patients

S Coppola, A Caccioppola, S Froio, P Formenti… - Critical Care, 2020 - Springer
Background In ARDS patients, mechanical ventilation should minimize ventilator-induced
lung injury. The mechanical power which is the energy per unit time released to the …

Perioperative pulmonary atelectasis: part I. Biology and mechanisms

C Zeng, D Lagier, JW Lee, MF Vidal Melo - Anesthesiology, 2022 - pubs.asahq.org
Pulmonary atelectasis is common in the perioperative period. Physiologically, it is produced
when collapsing forces derived from positive pleural pressure and surface tension overcome …

Mechanical power at a glance: a simple surrogate for volume-controlled ventilation

L Giosa, M Busana, I Pasticci, M Bonifazi… - Intensive care medicine …, 2019 - Springer
Background Mechanical power is a summary variable including all the components which
can possibly cause VILI (pressures, volume, flow, respiratory rate). Since the complexity of …

Ventilation-induced lung injury (VILI) in neonates: evidence-based concepts and lung-protective strategies

R Kalikkot Thekkeveedu, A El-Saie, V Prakash… - Journal of clinical …, 2022 - mdpi.com
Supportive care with mechanical ventilation continues to be an essential strategy for
managing severe neonatal respiratory failure; however, it is well known to cause and …

Power to mechanical power to minimize ventilator-induced lung injury?

PL Silva, L Ball, PRM Rocco, P Pelosi - Intensive care medicine …, 2019 - Springer
Mechanical ventilation is a life-supportive therapy, but can also promote damage to
pulmonary structures, such as epithelial and endothelial cells and the extracellular matrix, in …

Imaging in acute respiratory distress syndrome

A Pesenti, G Musch, D Lichtenstein, F Mojoli… - Intensive care …, 2016 - Springer
Purpose Imaging has become increasingly important across medical specialties for
diagnostic, monitoring, and investigative purposes in acute respiratory distress syndrome …

Global and regional diagnostic accuracy of lung ultrasound compared to CT in patients with acute respiratory distress syndrome

D Chiumello, M Umbrello, GFS Papa… - Critical care …, 2019 - journals.lww.com
Objectives: Lung CT is the reference imaging technique for acute respiratory distress
syndrome, but requires transportation outside the intensive care and x-ray exposure. Lung …