The baby lung and the COVID-19 era

L Gattinoni, K Meissner, JJ Marini - Intensive care medicine, 2020 - Springer
The concept of the baby lung was born in 1987 [1] when quantitative CT scan analysis
demonstrated that, in severe ARDS, the amount of the ventilatable lung tissue of an adult …

Latent class analysis to predict intensive care outcomes in Acute Respiratory Distress Syndrome: a proposal of two pulmonary phenotypes

PD Wendel Garcia, A Caccioppola, S Coppola, T Pozzi… - Critical Care, 2021 - Springer
Background Acute respiratory distress syndrome remains a heterogeneous syndrome for
clinicians and researchers difficulting successful tailoring of interventions and trials. To this …

Targeting transpulmonary pressure to prevent ventilator-induced lung injury

L Gattinoni, L Giosa, M Bonifazi, I Pasticci… - Expert review of …, 2019 - Taylor & Francis
Introduction: Transpulmonary pressure (PL) is the pressure distending the lung. This
pressure equals the stress which develops into the parenchyma at each insufflation and it …

Red cell distribution width/albumin ratio is associated with 60-day mortality in patients with acute respiratory distress syndrome

JW Yoo, S Ju, SJ Lee, YJ Cho, JD Lee… - Infectious …, 2020 - Taylor & Francis
Background: Red cell distribution width (RDW) and albumin concentration are associated
with clinical outcomes in patients with acute respiratory distress syndrome, but the clinical …

Severe hypoxemia: which strategy to choose

D Chiumello, M Brioni - Critical Care, 2016 - Springer
Background Acute respiratory distress syndrome (ARDS) is characterized by a
noncardiogenic pulmonary edema with bilateral chest X-ray opacities and reduction in lung …

Does regional lung strain correlate with regional inflammation in acute respiratory distress syndrome during nonprotective ventilation? An experimental porcine study

J Retamal, D Hurtado, N Villarroel, A Bruhn… - Critical Care …, 2018 - journals.lww.com
Objective: It is known that ventilator-induced lung injury causes increased pulmonary
inflammation. It has been suggested that one of the underlying mechanisms may be strain …

Prognostic values of the Berlin definition criteria, blood lactate level, and fibroproliferative changes on high-resolution computed tomography in ARDS patients

T Kamo, S Tasaka, T Suzuki, T Asakura… - BMC pulmonary …, 2019 - Springer
Abstract Background In the Berlin definition, acute respiratory distress syndrome (ARDS) is
stratified into three stages according to oxygenation severity at the onset. The relevance …

Radiological pattern in ARDS patients: partitioned respiratory mechanics, gas exchange and lung recruitability

S Coppola, T Pozzi, M Gurgitano, A Liguori… - Annals of Intensive …, 2021 - Springer
Background The ARDS is characterized by different degrees of impairment in oxygenation
and distribution of the lung disease. Two radiological patterns have been described: a focal …

[HTML][HTML] Emerging concepts in ventilation-induced lung injury

P Madahar, JR Beitler - F1000Research, 2020 - ncbi.nlm.nih.gov
Ventilation-induced lung injury results from mechanical stress and strain that occur during
tidal ventilation in the susceptible lung. Classical descriptions of ventilation-induced lung …

ERS statement on chest imaging in acute respiratory failure

D Chiumello, GFS Papa, A Artigas… - European …, 2019 - Eur Respiratory Soc
Chest imaging in patients with acute respiratory failure plays an important role in
diagnosing, monitoring and assessing the underlying disease. The available modalities …