Lung protection in acute respiratory distress syndrome: what should we target?

JR Beitler - Current opinion in critical care, 2020 - journals.lww.com
A precision medicine approach to lung-protective ventilation requires weighing four key
factors in each patient: biological predisposition to biophysical lung injury, mechanical …

The association between regional transcriptome profiles and lung volumes in response to mechanical ventilation and lung injury

Y Song, S Yen, M Preissner, E Bennett, S Dubsky… - Respiratory …, 2022 - Springer
Background Lung inhomogeneity plays a pivotal role in the development of ventilator-
induced lung injury (VILI), particularly in the context of pre-existing lung injury. The …

Dynamic hyperinflation and intrinsic positive end-expiratory pressure in ARDS patients

S Coppola, A Caccioppola, S Froio, E Ferrari, M Gotti… - Critical Care, 2019 - Springer
Background In ARDS patients, changes in respiratory mechanical properties and ventilatory
settings can cause incomplete lung deflation at end-expiration. Both can promote dynamic …

Gas exchange, specific lung elastance and mechanical power in the early and persistent ARDS

D Chiumello, S Froio, G Mistraletti, P Formenti… - Journal of Critical …, 2020 - Elsevier
Purpose Aim of this study was to evaluate the effect of acute respiratory distress syndrome
(ARDS) duration on gas-exchange, respiratory mechanics, specific lung elastance and …

The impact of reduction in intensity of mechanical ventilation upon venovenous ECMO initiation on radiographically assessed lung edema scores: a retrospective …

ET Worku, F Yeung, C Anstey, K Shekar - Frontiers in Medicine, 2022 - frontiersin.org
Background Patients with severe acute respiratory distress syndrome (ARDS) typically
receive ultra-protective ventilation after extracorporeal membrane oxygenation (ECMO) is …

[18F]FDG-PET/CT in mechanically ventilated critically ill patients with COVID-19 ARDS and persistent inflammation

B van Leer, JH van Snick, M Londema… - Clinical and translational …, 2023 - Springer
Purpose We report the findings of four critically ill patients who underwent an [18F] FDG-
PET/CT because of persistent inflammation during the late phase of their COVID-19 …

New frontiers in functional and molecular imaging of the acutely injured lung: pathophysiological insights and research applications

G Musch - Frontiers in Physiology, 2021 - frontiersin.org
This review focuses on the advances in the understanding of the pathophysiology of
ventilator-induced and acute lung injury that have been afforded by technological …

[引用][C] Minh C. Tran 1Ε, Douglas C. Crockett 1Ε, Tu K. Tran, Phi A. Phan 1Ε, Formenti Federico

R Bruce, G Perchiazzi, SJ Payne, AD Farmery - Scientific Reports, 2024

[HTML][HTML] Pneumomediastinum and pneumothorax in acute respiratory distress syndrome (ARDS) patients: a narrative review

YX Teo, HS Geetha, AK Mishra, A Lal - Mediastinum, 2024 - ncbi.nlm.nih.gov
Methods A search of the literature was conducted using PubMed, MEDLINE, and Google
Scholar for relevant articles pertaining to PNX and PMD in ARDS population. The clinical …

Mechanical power of ventilation and driving pressure: two undervalued parameters for pre extracorporeal membrane oxygenation ventilation and during daily …

K Hoppe, E Khan, P Meybohm, T Riese - Critical Care, 2023 - Springer
The current ARDS guidelines highly recommend lung protective ventilation which include
plateau pressure (P plat< 30 cm H2O), positive end expiratory pressure (PEEP> 5 cm H2O) …