Microglia activation is observed in various neurodegenerative diseases. Recent advances in
single-cell technologies have revealed that these reactive microglia were with high spatial …

Parkinson's disease (PD) is a common neurodegenerative disorder primarily characterized
by the death of dopaminergic neurons that project from the substantia nigra pars compacta …

Background: Parkinson's disease (PD) is an increasing challenge to public health. Tracking
the temporal trends of PD burden would inform health strategies. Methods: Data of PD …

Melatonin is ubiquitous molecule with wide distribution in nature and is produced by many
living organisms. In human beings, pineal gland is the major site for melatonin production …

Background Accumulating evidence links fine particulate matter (PM 2· 5) to premature
mortality, cardiovascular disease, and respiratory disease. However, less is known about the …

Parkinson's disease (PD) is the most common movement disorder with motor and nonmotor
signs. The current therapeutic regimen for PD is mainly symptomatic as the etio …

Since 2006, several longitudinal studies have assessed environmental or behavioural
factors that seem to modify the risk of developing Parkinson's disease. Increased risk of …

Parkinson's disease (PD) is a devastating and highly prevalent neurodegenerative disease
for which only symptomatic treatment is available. In order to develop a truly effective …

Background Emerging evidence suggests that living near major roads might adversely affect
cognition. However, little is known about its relationship with the incidence of dementia …

Parkinson disease (PD) is a progressive, neurodegenerative movement disorder with
symptoms reflecting various impairments and functional limitations, such as postural …