Exploring the role of neuropeptides in depression and anxiety
Depression is one of the most prevalent forms of mental disorders and is the most common
cause of disability in the Western world. Besides, the harmful effects of stress-related mood …
cause of disability in the Western world. Besides, the harmful effects of stress-related mood …
Role of neuropeptides in anxiety, stress, and depression: from animals to humans
Major depression, with its strikingly high prevalence, is the most common cause of disability
in communities of Western type, according to data of the World Health Organization. Stress …
in communities of Western type, according to data of the World Health Organization. Stress …
Glucocorticoid-driven NLRP3 inflammasome activation in hippocampal microglia mediates chronic stress-induced depressive-like behaviors
X Feng, Y Zhao, T Yang, M Song, C Wang… - Frontiers in molecular …, 2019 - frontiersin.org
Chronic stress is a key risk factor for depression, and microglia have been implicated in the
pathogenesis of the disease. Recent studies show that the Nod-like receptor protein 3 …
pathogenesis of the disease. Recent studies show that the Nod-like receptor protein 3 …
Unpredictable chronic mild stress not chronic restraint stress induces depressive behaviours in mice
The chronic stress model was developed on the basis of the stress–diathesis hypothesis of
depression. However, these behavioural responses associated with different stress …
depression. However, these behavioural responses associated with different stress …
Stress and opioids: role of opioids in modulating stress-related behavior and effect of stress on morphine conditioned place preference
Research studies have defined the important role of endogenous opioids in modulating
stress-associated behavior. The release of β-endorphins in the amygdala in response to …
stress-associated behavior. The release of β-endorphins in the amygdala in response to …
[HTML][HTML] Role of stress in skin diseases: a neuroendocrine-immune interaction view
H Zhang, M Wang, X Zhao, Y Wang, X Chen… - Brain, Behavior, and …, 2023 - Elsevier
Psychological stress is a crucial factor in the development of many skin diseases, and the
stigma caused by skin disorders may further increase the psychological burden, forming a …
stigma caused by skin disorders may further increase the psychological burden, forming a …
Depression as a neuroendocrine disorder: emerging neuropsychopharmacological approaches beyond monoamines
M Chávez-Castillo, V Núñez, M Nava… - Advances in …, 2019 - Wiley Online Library
Depression is currently recognized as a crucial problem in everyday clinical practice, in light
of ever‐increasing rates of prevalence, as well as disability, morbidity, and mortality related …
of ever‐increasing rates of prevalence, as well as disability, morbidity, and mortality related …
Are neuropeptides relevant for the mechanism of action of SSRIs?
M Gołyszny, E Obuchowicz - Neuropeptides, 2019 - Elsevier
Selective serotonin reuptake inhibitors (SSRIs) are drugs of first choice in the therapy of
moderate to severe depression and anxiety disorders. Their primary mechanism of action is …
moderate to severe depression and anxiety disorders. Their primary mechanism of action is …
[HTML][HTML] Noradrenergic modulation of stress resilience
Resilience represents an active adaption process in the face of adversity, trauma, tragedy,
threats, or significant sources of stress. Investigations of neurobiological mechanisms of …
threats, or significant sources of stress. Investigations of neurobiological mechanisms of …
Galanin promotes autophagy and alleviates apoptosis in the hypertrophied heart through FoxO1 pathway
I Martinelli, A Timotin, P Moreno-Corchado, D Marsal… - Redox biology, 2021 - Elsevier
Autophagy and apoptosis are powerful regulators of multiple facets of cellular metabolism
and homeostasis. Here, we uncover that galanin, a pleiotropic peptide, regulates cardiac …
and homeostasis. Here, we uncover that galanin, a pleiotropic peptide, regulates cardiac …