Leishmaniasis in humans: drug or vaccine therapy?

M Ghorbani, R Farhoudi - Drug design, development and therapy, 2017 - Taylor & Francis
Leishmania is an obligate intracellular pathogen that invades phagocytic host cells.
Approximately 30 different species of Phlebotomine sand flies can transmit this parasite …

Cutaneous leishmaniasis

R Reithinger, JC Dujardin, H Louzir… - The Lancet infectious …, 2007 - thelancet.com
Cutaneous leishmaniasis is endemic in the tropics and neotropics. It is often referred to as a
group of diseases because of the varied spectrum of clinical manifestations, which range …

Possibilities and challenges for developing a successful vaccine for leishmaniasis

S Srivastava, P Shankar, J Mishra, S Singh - Parasites & vectors, 2016 - Springer
Leishmaniasis is a vector-borne disease caused by different species of protozoan parasites
of the genus Leishmania. It is a major health problem yet neglected tropical diseases, with …

[HTML][HTML] How effective is dog culling in controlling zoonotic visceral leishmaniasis? A critical evaluation of the science, politics and ethics behind this public health …

CHN Costa - Revista da Sociedade Brasileira de Medicina Tropical, 2011 - SciELO Brasil
INTRODUCTION: Zoonotic kala-azar, a lethal disease caused by protozoa of the genus
Leishmania is considered out of control in parts of the world, particularly in Brazil, where …

Vaccines for leishmaniasis in the fore coming 25 years

CB Palatnik-de-Sousa - Vaccine, 2008 - Elsevier
Human vaccination against leishmaniasis using live Leishmania was used in Middle East
and Russia (1941–1980). First-generation vaccines, composed by killed parasites induce …

Vaccine candidates for leishmaniasis: a review

R Nagill, S Kaur - International immunopharmacology, 2011 - Elsevier
Leishmaniasis is a diverse group of clinical syndromes caused by protozoan parasites of the
genus Leishmania. The clinical manifestation of the disease varies from self-limiting …

First generation leishmaniasis vaccines: a review of field efficacy trials

S Noazin, F Modabber, A Khamesipour, PG Smith… - Vaccine, 2008 - Elsevier
First generation candidate vaccines against leishmaniasis, prepared using inactivated
whole parasites as their main ingredient, were considered as promising because of their …

[HTML][HTML] Vaccination in leishmaniasis: a review article

L Abdellahi, F Iraji, A Mahmoudabadi… - Iranian Biomedical …, 2022 - ncbi.nlm.nih.gov
Leishmaniasis is caused by protozoan Leishmania parasites that are transmitted through
female sandfly bites. The disease is predominantly endemic to the tropics and semi-tropics …

New World cutaneous leishmaniasis: updated review of current and future diagnosis and treatment

P Mitropoulos, P Konidas, M Durkin-Konidas - Journal of the American …, 2010 - Elsevier
BACKGROUND: Cutaneous leishmaniasis (CL) has traditionally been underrecognized and
underreported. Improved awareness is warranted as the number of cases has increased as …

A review of preventative methods against human leishmaniasis infection

L Stockdale, R Newton - PLoS neglected tropical diseases, 2013 - journals.plos.org
Background Leishmaniasis is an intracellular parasitic infection transmitted to humans via
the sandfly. Approximately 350 million people are at risk of contracting the disease and an …