Carbohydrates, fats, and proteins are the underlying energy sources for animals and are
catabolized through specific biochemical cascades involving numerous enzymes. The …

Bone is a dynamic tissue and is constantly being remodeled by bone cells. Metabolic
reprogramming plays a critical role in the activation of these bone cells and skeletal …

Background: Overexposure to glucocorticoid (GC) produces various clinical complications,
including osteoporosis (OP), dyslipidemia, and hypercholesterolemia. Geniposide (GEN) is …

Osteoporosis is a systemic bone‐resorbing disease that easily causes subsequent risk of
fracture. Hence, the substantial physical burden of osteoporosis makes it an important public …

Background Numerous studies have confirmed that atherosclerosis is related to
osteoporosis (OP), and patients with atherosclerosis are more prone to OP. The ratio of low …

Objective Little is known about whether diabetic dyslipidaemia contributes to increased
bone fragility in patients with diabetes. This study aimed to explore the potential effects of …

We aimed to compare the time-course effect of D-galactose (D-gal)-induced aging, obesity,
and their combined effects on bone homeostasis. Male Wistar rats were fed with either a …

Context Osteoporosis (OP) is a metabolic disease. We have previously demonstrated that
aucubin (AU) has anti-OP effects that are due to its promotion of the formation of osteoblasts …

Osteoporosis is a common bone metabolic disease that causes a heavy social burden and
seriously threatens life. Improving osteogenic capacity is necessary to correct bone mass …

Background. Results of animal studies show that a high-cholesterol diet increases bone
resorption and decreases bone formation, thus leading to osteoporosis. Previously, we …