An ideal vascular substitute, especially in< 6 mm diameter applications, is a major clinical
essentiality in blood vessel replacement surgery. Blood vessels are structurally complex and …

Biomaterials with the capacity to innately guide cell behaviour while also displaying suitable
mechanical properties remain a challenge in tissue engineering. Our approach to this has …

In situ tissue engineering using bioresorbable material implants-or scaffolds-that harness
the patient's immune response while guiding neotissue formation at the site of implantation …

The development of vascular grafts has focused on finding a biomaterial that is non-
thrombogenic, minimizes intimal hyperplasia, matches the mechanical properties of native …

Elastin provides structural integrity, biological cues and persistent elasticity to a range of
important tissues, including the vasculature and lungs. Its critical importance to normal …

Designing a biomimetic and functional tissue-engineered vascular graft has been urgently
needed for repairing and regenerating defected vascular tissues. Utilizing a multi-layered …

The endothelial cells (ECs) that line the inner layer of blood vessels are responsible for
maintaining vascular homeostasis under physiological conditions. In the presence of …

Vascular tissue engineering is a relevant research field aimed at elaborating and proposing
innovative solutions to overcome the drawbacks related to the use of conventional blood …

In search for novel biomimetic scaffolds for application in vascular tissue engineering, we
evaluated a series of fibrous scaffolds prepared by coelectrospinning tertiary blends of poly …

Abstract Development of electrospun nanofibers that mimic the structural, mechanical and
biochemical properties of natural extracellular matrices (ECMs) is a promising approach for …