Enhancing osteoporosis treatment with engineered mesenchymal stem cell-derived extracellular vesicles: mechanisms and advances

Y Chen, Y Huang, J Li, T Jiao, L Yang - Cell Death & Disease, 2024 - nature.com
As societal aging intensifies, the incidence of osteoporosis (OP) continually rises. OP is a
skeletal disorder characterized by reduced bone mass, deteriorated bone tissue …

Therapeutic potential of mesenchymal stem cell-derived exosomes in skeletal diseases

X Yang, S Zhang, J Lu, X Chen, T Zheng… - Frontiers in Molecular …, 2024 - frontiersin.org
Skeletal diseases impose a considerable burden on society. The clinical and tissue-
engineering therapies applied to alleviate such diseases frequently result in complications …

Clinical Applications of Adipose-Derived Stem Cell (ADSC) Exosomes in Tissue Regeneration

KS Papadopoulos, C Piperi… - International Journal of …, 2024 - mdpi.com
Adipose-derived stem cells (ADSCs) are mesenchymal stem cells with a great potential for
self-renewal and differentiation. Exosomes derived from ADSCs (ADSC-exos) can imitate …

Non-bone-derived exosomes: a new perspective on regulators of bone homeostasis

P Wang, W Shao, Z Li, B Wang, X Lv, Y Huang… - Cell Communication and …, 2024 - Springer
Accumulating evidence indicates that exosomes help to regulate bone homeostasis. The
roles of bone-derived exosomes have been well-described; however, recent studies have …

[HTML][HTML] Nrf2 activation: a key mechanism in stem cell exosomes-mediated therapies

Z Vahidinia, A Azami Tameh, S Barati… - Cellular & Molecular …, 2024 - Springer
Exosomes are nano-sized membrane extracellular vesicles which can be released from
various types of cells. Exosomes originating from inflammatory or injured cells can have …

Regulation of the Nrf2/HO-1 axis by mesenchymal stem cells-derived extracellular vesicles: implications for disease treatment

H Su, Z Wang, L Zhou, D Liu, N Zhang - Frontiers in Cell and …, 2024 - frontiersin.org
This comprehensive review inspects the therapeutic potential of mesenchymal stem cell-
derived extracellular vesicles (MSC-EVs) across multiple organ systems. Examining their …