A comprehensive overview on stress neurobiology: basic concepts and clinical implications

LD Godoy, MT Rossignoli, P Delfino-Pereira… - Frontiers in behavioral …, 2018 - frontiersin.org
Stress is recognized as an important issue in basic and clinical neuroscience research,
based upon the founding historical studies by Walter Canon and Hans Selye in the past …

The anticonvulsant effects of cannabidiol in experimental models of epileptic seizures: From behavior and mechanisms to clinical insights

W Lazarini-Lopes, RA Do Val-da Silva… - Neuroscience & …, 2020 - Elsevier
Epilepsy is a neurological disorder characterized by the presence of seizures and
neuropsychiatric comorbidities. Despite the number of antiepileptic drugs, one-third of …

Parvalbumin role in epilepsy and psychiatric comorbidities: from mechanism to intervention

LD Godoy, T Prizon, MT Rossignoli, JP Leite… - Frontiers in Integrative …, 2022 - frontiersin.org
Parvalbumin is a calcium-binding protein present in inhibitory interneurons that play an
essential role in regulating many physiological processes, such as intracellular signaling …

Zinc signaling and epilepsy

U Doboszewska, K Młyniec, A Wlaź, E Poleszak… - Pharmacology & …, 2019 - Elsevier
Evidence from both preclinical and clinical studies suggest the importance of zinc
homeostasis in seizures/epilepsy. Undoubtedly, zinc, via modulation of a variety of targets, is …

Deep learning approaches for seizure video analysis: A review

D Ahmedt-Aristizabal, MA Armin, Z Hayder… - Epilepsy & Behavior, 2024 - Elsevier
Seizure events can manifest as transient disruptions in the control of movements which may
be organized in distinct behavioral sequences, accompanied or not by other observable …

A complex systems view on the current hypotheses of epilepsy pharmacoresistance

G Servilha‐Menezes, N Garcia‐Cairasco - Epilepsia Open, 2022 - Wiley Online Library
Drug‐resistant epilepsy remains to this day as a highly prevalent condition affecting around
one‐third of patients with epilepsy, despite all the research and the development of several …

Rodent brain pathology, audiogenic epilepsy

IB Fedotova, NM Surina, GM Nikolaev, AV Revishchin… - Biomedicines, 2021 - mdpi.com
The review presents data which provides evidence for the internal relationship between the
stages of rodent audiogenic seizures and post-ictal catalepsy with the general pattern of …

Increased TRPV1 channels and FosB protein expression are associated with chronic epileptic seizures and Anxiogenic-like behaviors in a preclinical model of …

W Lazarini-Lopes, GK Silva-Cardoso… - Biomedicines, 2022 - mdpi.com
Epilepsies are neurological disorders characterized by chronic seizures and their related
neuropsychiatric comorbidities, such as anxiety. The Transient Receptor Potential Vanilloid …

Transcriptome of the Krushinsky-Molodkina audiogenic rat strain and identification of possible audiogenic epilepsy-associated genes

LN Chuvakova, SY Funikov, AP Rezvykh… - Frontiers in Molecular …, 2021 - frontiersin.org
Audiogenic epilepsy (AE), inherent to several rodent strains is widely studied as a model of
generalized convulsive epilepsy. The molecular mechanisms that determine the …

Analysis of gene variants in the GASH/Sal model of epilepsy

E Díaz-Casado, R Gómez-Nieto, JM de Pereda… - PLoS …, 2020 - journals.plos.org
Epilepsy is a complex neurological disorder characterized by sudden and recurrent
seizures, which are caused by various factors, including genetic abnormalities. Several …