Clinical delivery of circular RNA: lessons learned from RNA drug development
Circular RNAs (circRNA) represent a distinct class of covalently closed-loop RNA molecules,
which play diverse roles in regulating biological processes and disease states. The …
which play diverse roles in regulating biological processes and disease states. The …
[HTML][HTML] Exosome-based nanoimmunotherapy targeting TAMs, a promising strategy for glioma
H Luo, H Zhang, J Mao, H Cao, Y Tao, G Zhao… - Cell Death & …, 2023 - nature.com
Exosomes, the cell-derived small extracellular vehicles, play a vital role in intracellular
communication by reciprocally transporting DNA, RNA, bioactive protein, chains of glucose …
communication by reciprocally transporting DNA, RNA, bioactive protein, chains of glucose …
Emerging digital PCR technology in precision medicine
L Zhang, R Parvin, Q Fan, F Ye - Biosensors and Bioelectronics, 2022 - Elsevier
Digital PCR (dPCR) is built on partitioning reagent to the extent that single template
molecules are amplified and visualized individually, whereby offers higher precision and …
molecules are amplified and visualized individually, whereby offers higher precision and …
[HTML][HTML] Upconversion nanoparticles for super-resolution quantification of single small extracellular vesicles
Although small EVs (sEVs) have been used widely as biomarkers in disease diagnosis, their
heterogeneity at single EV level has rarely been revealed. This is because high-resolution …
heterogeneity at single EV level has rarely been revealed. This is because high-resolution …
Bimetallic Metal–Organic Framework Fe/Co-MIL-88(NH2) Exhibiting High Peroxidase-like Activity and Its Application in Detection of Extracellular Vesicles
Metal–organic frameworks (MOFs) have many attractive features, including tunable
composition, rigid structure, controllable pore size, and large specific surface area, and thus …
composition, rigid structure, controllable pore size, and large specific surface area, and thus …
[HTML][HTML] Artificial exosomes for translational nanomedicine
YJ Li, JY Wu, J Liu, W Xu, X Qiu, S Huang… - Journal of …, 2021 - Springer
Exosomes are lipid bilayer membrane vesicles and are emerging as competent
nanocarriers for drug delivery. The clinical translation of exosomes faces many challenges …
nanocarriers for drug delivery. The clinical translation of exosomes faces many challenges …
Exomeres: A new member of extracellular vesicles family
Extracellular vesicles (EVs) are described as membranous vesicles that are secreted by
various cell types. EVs can be categorised as exosomes, ectosomes, apoptotic bodies, large …
various cell types. EVs can be categorised as exosomes, ectosomes, apoptotic bodies, large …
[HTML][HTML] Multiplexed profiling of extracellular vesicles for biomarker development
Extracellular vesicles (EVs) are cell-derived membranous particles that play a crucial role in
molecular trafficking, intercellular transport and the egress of unwanted proteins. They have …
molecular trafficking, intercellular transport and the egress of unwanted proteins. They have …
Responsive sensors of upconversion nanoparticles
Upconversion nanoparticles are a class of luminescent materials that convert longer-
wavelength near-infrared photons into visible and ultraviolet emissions. They can respond to …
wavelength near-infrared photons into visible and ultraviolet emissions. They can respond to …
Comparison of curative effect of human umbilical cord-derived mesenchymal stem cells and their small extracellular vesicles in treating osteoarthritis
S Tang, P Chen, H Zhang, H Weng, Z Fang… - International journal …, 2021 - Taylor & Francis
Introduction Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) and their
small extracellular vesicles (hUC-MSC-sEVs) have shown attractive prospects applying in …
small extracellular vesicles (hUC-MSC-sEVs) have shown attractive prospects applying in …