Meiosis is the basis of sexual reproduction. In female mammals, meiosis of oocytes starts
before birth and sustains at the dictyate stage of meiotic prophase I before gonadotropins …

In vitro fertilization (IVF) is currently one of the most effective methods of infertility treatment.
An alternative to commonly used ovarian hyperstimulation can become extracorporeal …

BACKGROUND A large number of studies have contributed to understanding the general
mechanisms driving ovarian folliculogenesis in humans and show a complex endocrine …

Female fertility is determined to a large extent by the quality (developmental competence) of
the oocyte as reflected in its ability to undergo meiosis, be fertilized, and give rise to a …

Polycystic ovary syndrome (PCOS) is typically characterized by a polycystic ovarian
morphology, hyperandrogenism, ovulatory dysfunction, and infertility. Furthermore, PCOS …

Production of functional eggs requires meiosis to be coordinated with developmental
signals. Oocytes arrest in prophase I to permit oocyte differentiation, and in most animals, a …

BACKGROUND Dialogue between the oocyte and cumulus cells is essential for oocyte
maturation. A prospective laboratory research project was designed to evaluate transcription …

Oocyte developmental competence is one of the determining factors that influence the
outcomes of an IVF cycle regarding the ability of a female gamete to reach maturation, be …

Mammalian oocytes arrest at prophase of meiosis I at around birth and they remain arrested
at this stage until puberty when the preovulatory surge of luteinizing hormone (LH) causes …

The spindle assembly checkpoint (SAC) monitors attachment to microtubules and tension on
chromosomes in mitosis and meiosis. It represents a surveillance mechanism that halts cells …