Binding elucidation of azo dyes with human serum albumin via spectroscopic approaches and molecular docking techniques

A Mousazadeh Moghaddam Pour… - Journal of …, 2023 - Taylor & Francis
The large number of synthesized azo dyes is widely applied in the food, pharmaceutical,
cosmetic, textile, and leather industries. In this study, the binding mechanism of two …

Spectral and computational attributes: Binding of a potent anticancer agent, dasatinib to a transport protein

R Naik, S Jaldappagari - Journal of Molecular Liquids, 2019 - Elsevier
The present study describes the insights in to the mechanism of interaction between a model
protein and an anticancer drug, dasatinib (DAS). DAS is a multi-target anticancer drug which …

[HTML][HTML] Effect of Zuoguiwan on osteoporosis in ovariectomized rats through RANKL/OPG pathway mediated by β2AR

F Liu, F Tan, W Tong, Q Fan, S Ye, S Lu, Z Teng… - Biomedicine & …, 2018 - Elsevier
Ethnopharmacological relevance The deficiency of kidney Yin is the main pathogenesis of
postmenopausal osteoporosis (PMOP) according to traditional Chinese medicine (TCM) …

Biophysical and computational comparison on the binding affinity of three important nutrients to β-lactoglobulin: folic acid, ascorbic acid and vitamin K3

S Shahraki, A Heydari, M Saeidifar… - Journal of Biomolecular …, 2018 - Taylor & Francis
Small globular protein, β-lactoglobulin (βLG), which has significant affinity toward many
drugs, is the most abundant whey protein in milk. In this study, the interaction of βLG with …

Molecular dynamics simulation as a tool for assessment of drug binding property of human serum albumin

M Narwal, D Kumar, TK Mukherjee… - Molecular biology …, 2018 - Springer
Human serum albumin (HSA) is a major plasma protein and binding of drugs with this
plasma protein has a great importance. It possess esterase activity which can cleave the …

Insights into the binding mechanism of a model protein with fomesafen: Spectroscopic studies, thermodynamics and molecular modeling exploration

X Dong, L Wang, R Feng, Z Ren, L Zhang… - Journal of Molecular …, 2019 - Elsevier
The long residual period and toxicity of fomesafen makes it accumulating in the environment
as environmental pollutant. Bovine serum albumin (BSA) plays an indispensable role in the …

Evidence for paraquat-pepsin interaction: In vitro and silico study

N Farokhvand, B Shareghi, S Farhadian - Chemosphere, 2024 - Elsevier
The use of the herbicide paraquat (PQ) has raised concerns about potential environmental
consequences due to its toxicity and persistence in the environment. Considering the affinity …

Evaluation of the toxicity of 5-fluorouracil on three digestive enzymes from the view of side effects

Y Wang, Q Han, H Zhang - Spectrochimica Acta Part A: Molecular and …, 2019 - Elsevier
Among the side effects of 5-fluorouracil (5-FU), the performance of the gastrointestinal
reactions is faster and more obvious than others. In this work, the effects of 5-FU on the …

Computational and experimental study on the interaction of three novel rare earth complexes containing 2, 9-dimethyl-1, 10-phenanthroline with human serum …

Z Aramesh-Boroujeni, AK Bordbar… - Journal of the Iranian …, 2018 - Springer
In this paper, several rare earth [terbium (III), ytterbium (III) and yttrium (III)] complexes
containing 2, 9-dimethyl-1, 10-phenanthroline (Me 2 Phen) were successfully synthesized …

A red-emitting fluorescent probe with large Stokes shift for real-time tracking of cysteine over glutathione and homocysteine in living cells

M Qian, L Zhang, J Wang, X Peng - Spectrochimica Acta Part A: Molecular …, 2019 - Elsevier
Fluorescent probes with high quality for highly selective detection of cysteine (Cys) are still
urgently in demand because of the indispensable roles Cys plays in the biological systems …