High-throughput methods for slide-free three-dimensional (3D) pathological analyses of
whole biopsies and surgical specimens offer the promise of modernizing traditional …

Breast cancer is the most prevalent malignant tumor and main oncologic cause of mortality
in women. Although most diagnosis of breast pathology is accomplished using hematoxylin …

During metastasis, malignant cells escape the primary tumor, intravasate lymphatic vessels,
and reach draining sentinel lymph nodes before they colonize distant organs via the blood …

Background We determined the prognostic impact of lymphovascular invasion (LVI) in a
large, national, multicenter, retrospective cohort of patients with early breast cancer (BC) …

Lymphatic metastasis is the main prognostic factor for survival of patients with breast cancer
and other epithelial malignancies. Mounting clinical and experimental data suggest that …

It was already in the 18th century when the French surgeon LeDran first noted that breast
cancer patients with spread of tumor cells to their axillary lymph nodes had a drastically …

Metastasis is a major cause of death in patients with cancer. The two main routes for cancer
cell dissemination are the blood and lymphatic systems. The underlying mechanism of …

Introduction IL-17 plays an important role in autoimmunity, promoting autoimmunity,
inflammation and invasion in multiple sclerosis, rheumatoid arthritis and type I diabetes. The …

Breast cancer remains the leading cause of cancer mortality worldwide, despite a significant
decline in death rates due to early detection. The majority of cancer mortalities are due to the …

BACKGROUND: The European Association of Urology (EAU) guidelines advise an elective
bilateral lymphadenectomy in clinically node-negative (cN0) patients with high-risk penile …