Targeting progesterone receptors in newborn males and females: From the animal model to a new perspective for the treatment of apnea of prematurity?

A Bairam, R Boukari, V Joseph - Respiratory Physiology & Neurobiology, 2019 - Elsevier
The steroid hormone progesterone is well-known for its role in neuroprotection, in the pre-
and postnatal brain development, and is also recognized as a potent respiratory stimulant …

Maturation of cardioventilatory physiological trajectories in extremely preterm infants

DE Weese-Mayer, JM Di Fiore, DE Lake, AM Hibbs… - Pediatric …, 2024 - nature.com
Background In extremely preterm infants, persistence of cardioventilatory events is
associated with long-term morbidity. Therefore, the objective was to characterize physiologic …

Maternal distress during pregnancy and recurrence in early childhood predicts atopic dermatitis and asthma in childhood

AP van der Leek, S Bahreinian, M Chartier, ME Dahl… - Chest, 2020 - Elsevier
Background Early-life stress is becoming an important determinant of immune system
programming. Maternal prenatal distress is found to be associated with atopic disease in …

The epidemiology of apnoea of prematurity

JV Pergolizzi Jr, P Fort, TL Miller… - Journal of clinical …, 2022 - Wiley Online Library
What is known and objective Many premature infants less than 37 weeks gestational age
(GA), and almost all infants less than 28 weeks GA, will experience apnoea of prematurity …

NAVA—synchronized compared to nonsynchronized noninvasive ventilation for apnea, bradycardia, and desaturation events in VLBW infants

CR Tabacaru, RR Moores Jr, J Khoury… - Pediatric …, 2019 - Wiley Online Library
Neurally adjusted ventilatory assistance (NAVA) can overcome technical difficulties with
synchronizing noninvasive ventilation breaths with the patient, a modality often used in very …

Targeting the Toll-like receptor pathway as a therapeutic strategy for neonatal infection

ML Dias, KM O'Connor, EM Dempsey… - American Journal …, 2021 - journals.physiology.org
Toll-like receptors (TLRs) are crucial transmembrane receptors that form part of the innate
immune response. They play a role in the recognition of various microorganisms and their …

Erythropoietin and caffeine exert similar protective impact against neonatal intermittent hypoxia: Apnea of prematurity and sex dimorphism

S Laouafa, P Iturri, C Arias-Reyes, F Marcouiller… - Experimental …, 2019 - Elsevier
Apnea of prematurity (AoP) is associated with severe and repeated episodes of arterial
oxygen desaturation (intermittent hypoxia-IH), which in turn increases the number of apneas …

Therapeutic drug monitoring of caffeine and its primary metabolites in plasma using LC–ESI–MS/MS for apnea of prematurity treatment: Evaluation of ultrapure water …

JY Long, YH Hu, Y Xia, FF Du, HR Dai… - Biomedical …, 2022 - Wiley Online Library
The growing evidence has endorsed the view that therapeutic drug monitoring of caffeine for
apnea of prematurity is helpful for dose tailoring when the therapeutic response is lacking or …

The impact of preterm adversity on cardiorespiratory function

FB McDonald, EM Dempsey… - Experimental …, 2020 - Wiley Online Library
New Findings What is the topic of this review? We review the influence of prematurity on the
cardiorespiratory system and examine the common sequel of alterations in oxygen tension …

Late effects of caffeine use on sleep of infants born prematurely

ACN Oliveira, APCC Leão, AL Goulart… - Revista Paulista de …, 2023 - SciELO Brasil
Objective: This study aimed to evaluate whether the therapeutic use of caffeine for
premature newborns is associated with changes in sleep habits and the presence of …