Second-line switch to dolutegravir for treatment of HIV infection

LA Ombajo, J Penner, J Nkuranga… - … England Journal of …, 2023 - Mass Medical Soc
Background Data to inform the switch from a ritonavir-boosted protease inhibitor (PI) to
dolutegravir in patients living with human immunodeficiency virus (HIV) infection who do not …

HIV-1 subtype diversity and factors affecting drug resistance among patients with virologic failure in antiretroviral therapy in Hainan province, China, 2014–2020

YU De E, YJ Xu, LI Mu, Y Yuan, HY Liang… - Biomedical and …, 2023 - Elsevier
Objective This study aimed to determine the HIV-1 subtype distribution and HIV drug
resistance (HIVDR) in patients with ART failure from 2014 to 2020 in Hainan, China …

Factors associated with viral load non-suppression among treatment-experienced pre-teenage children living with HIV in Kenya: a nationwide population-based …

MM Mulinge, NK Kibui, H Kimani, J Wainaina… - …, 2024 - thelancet.com
Background Viral load non-suppression (VLNS) in children is a major public health concern
because of attendant HIV disease progression and risk of morbidity and mortality. Based on …

Early warning indicators of HIV drug resistance in the southern highlands region of Tanzania: Lessons from a cross-sectional surveillance study

SA Khamadi, C Mavere, E Bahemana… - PLOS Global Public …, 2023 - journals.plos.org
The World Health Organization early warning indicators (EWIs) permit surveillance of factors
associated with the emergence of HIV drug resistance (HIVDR). We examined cross-and …

[HTML][HTML] Net charge and position 22 of the V3 loop are associated with HIV-1 tropism in recently infected female sex workers in Nairobi, Kenya

HK Abisi, LE Otieno, E Irungu, FG Onyambu… - Medicine, 2022 - journals.lww.com
Human immunodeficiency virus (HIV) infection affects around 37 million people worldwide,
and in Kenya, key populations especially female sex workers (FSW), are thought to play a …

[HTML][HTML] Age and CD4+ T cell counts are inversely associated with HIV drug resistance mutations in treatment naive female sex workers

MM Mulinge, JO Oluoch, HK Abisi, LE Otieno… - Medicine, 2023 - journals.lww.com
The increasing prevalence of human immunodeficiency virus (HIV) drug resistance
mutations (HIVDRM) in untreated seropositive persons has consequences for future …

Virologic Nonsuppression and HIV Drug Resistance Among People Who Inject Drugs and Their Sexual and Injecting Partners in Kenya

BH Chohan, H Kingston, AS Tseng… - AIDS Research and …, 2024 - liebertpub.com
We evaluated the prevalence and correlates of HIV viral nonsuppression and HIV drug
resistance (HIV-DR) in a cohort of people who inject drugs living with HIV (PWID-LH) and …

A Machine Learning Approach to Predict HIV Viral Load Hotspots in Kenya Using Real-World Data

N Kagendi, M Mwau - Health Data Science, 2023 - spj.science.org
Background Machine learning models are not in routine use for predicting HIV status. Our
objective is to describe the development of a machine learning model to predict HIV viral …

HIV-1 drug resistance-associated mutations in relation to viral load among HIV/AIDS patients at Dr. M. Djamil-Hospital Padang

R Nadia, D Elvira, R Raveinal - Universa Medicina, 2024 - univmed.org
Background According to the WHO, 38 million people suffer from HIV worldwide and
according to the HIV Drug Resistance Report, the prevalence of antiretroviral therapy (ART) …

Impact of sex work and behavior on the immunological milieu of young female sex workers in Mombasa, Kenya.

R Mwatelah - 2024 - mspace.lib.umanitoba.ca
HIV disproportionately affects adolescent girls and young women in Sub-saharan Africa and
having a diverse microbiome has been associated with an increased risk of HIV acquisition …