Atopic dermatitis (AD) is a common and relapsing skin disease that is characterized by skin
barrier dysfunction, inflammation, and chronic pruritus. While AD was previously thought to …

Although, drugs are required in the various skin compartments such as viable epidermis,
dermis, or hair follicles, to efficiently treat skin diseases, drug delivery into and across the …

Atopic dermatitis is a common, chronic inflammatory skin disease that is characterized by
skin barrier dysfunction, inflammation and intense itch. Although the exact mechanisms …

The skin is a unique immune organ that constitutes a complex network of physical, chemical
and microbiological barriers against external insults. Keratinocytes are the most abundant …

Introduction Epidemiological studies demonstrated that cleaning work and frequent use of
cleaning products are risk factors for asthma. Laundry detergents have been reported to …

abstract Atopic dermatitis (AD) is the most common chronic skin inflammatory disease, with a
profound impact on patients' quality of life. AD varies considerably in clinical course, age of …

Tight junctions (TJs) are crucial for intercellular connections. The abnormal expression of
proteins related to TJs can result in TJ destruction, structural damage, and endothelial and …

The percutaneous device dilemma describes etiological factors, centered around the
disrupted epithelial tissue surrounding non-remodelable devices, that contribute to rampant …

Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD). Its etiology is unclear.
Much evidence suggests that the death of abnormal intestinal epithelial cells (IECs) leads to …

Atopic dermatitis (AD) is associated with cutaneous dysbiosis, barrier defects, and immune
dysregulation, but the interplay between these factors needs further study. Early-onset …