Qing-Re-Chu-shi decoction ameliorates 2, 4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice through anti-inflammation and immunoregulatory …

YJ Meng, Y Liu, J Guo, X Guo, X Han, L Zhang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Qing-Re-Chu-Shi Decoction (QRCSD), a
traditional Chinese herbal formula, has been employed as a complementary and alternative …

A sustainable strategy for generating highly stable human skin equivalents based on fish collagen

SH Tan, S Liu, SH Teoh, C Bonnard, D Leavesley… - Biomaterials …, 2024 - Elsevier
Tissue engineered skin equivalents are increasingly recognized as potential alternatives to
traditional skin models such as human ex vivo skin or animal skin models. However, most of …

[HTML][HTML] Relevance of coding variation in FLG and DOCK8 in finnish pediatric patients with early-onset moderate-to-severe atopic dermatitis

M Perälä, M Kaustio, A Salava, E Jakkula, AS Pelkonen… - JID Innovations, 2023 - Elsevier
Early-onset, persistent atopic dermatitis (AD) is proposed as a distinct subgroup that may
have specific genotypic features. FLG gene loss-of-function variants are the best known …

[HTML][HTML] Bilateral deficiency of Meissner corpuscles and papillary microvessels in patients with acute complex regional pain syndrome

K Mehling, J Becker, J Chen, S Scriba, G Kindl… - Pain, 2024 - journals.lww.com
Complex regional pain syndrome (CRPS) presents postinjury with disproportionate pain and
neuropathic, autonomic, motor symptoms, and skin texture affection. However, the origin of …

[HTML][HTML] Inhibition of COX-2 signaling favors E. coli during urinary tract infection

S Mohanty, C Lindelauf, JK White, A Scheffschick… - Journal of …, 2023 - Springer
Background To avoid the overuse of antibiotics, non-steroidal anti-inflammatory drugs
(NSAIDs), acting via cyclooxygenase (COX) inhibition, have been used to reduce pain and …

[HTML][HTML] Skin barrier-inflammatory pathway is a driver of the psoriasis-atopic dermatitis transition

S Dong, D Li, D Shi - Frontiers in Medicine, 2024 - frontiersin.org
As chronic inflammatory conditions driven by immune dysregulation are influenced by
genetics and environment factors, psoriasis and atopic dermatitis (AD) have traditionally …

Preclinical Models of Atopic Dermatitis Suitable for Mechanistic and Therapeutic Investigations

AR Maskey, X Mo, XM Li - Journal of Inflammation Research, 2024 - Taylor & Francis
Atopic dermatitis (AD) is a complex immune-mediated abnormality of the skin characterized
by impaired barrier function, eczematous dermatitis, chronic pruritus and itch. The …

Dapagliflozin prevents reproductive damage caused by acute systemic inflammation through antioxidant, anti‐inflammatory, and antiapoptotic mechanisms

S Topsakal, O Ozmen, H Asci, A Gulal… - Basic & clinical …, 2024 - Wiley Online Library
Dapagliflozin (DPG) is a sodium‐glucose cotransporter‐2 (SGLT2) inhibitor that has been
suggested to possess anti‐inflammatory properties in diabetes. The aim of this study is to …

OBP2A regulates epidermal barrier function and protects against cytotoxic small hydrophobic molecules

S Nakanishi, T Hasegawa, K Maeno, A Motoyama… - iScience, 2024 - cell.com
The skin is constantly exposed to environmental sensory stimuli, which may include harmful
volatiles and small hydrophobic molecules. However, the skin's protective mechanism …

Claudins in Cancer: A Current and Future Therapeutic Target

C Hana, NN Thaw Dar, M Galo Venegas… - International Journal of …, 2024 - mdpi.com
Claudins are a family of 27 proteins that have an important role in the formation of tight
junctions. They also have an important function in ion exchange, cell mobility, and the …