Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms
YQ He, CC Zhou, LY Yu, L Wang, J Deng… - Pharmacological …, 2021 - Elsevier
Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome
(ARDS) as common life-threatening lung diseases with high mortality rates are mostly …
(ARDS) as common life-threatening lung diseases with high mortality rates are mostly …
An overview of anti-SARS-CoV-2 and anti-inflammatory potential of baicalein and its metabolite baicalin: insights into molecular mechanisms
Abstract The current Coronavirus Disease 2019 (COVID-19) pandemic, caused by the
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is highly contagious …
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is highly contagious …
[HTML][HTML] Xanthohumol ameliorates lipopolysaccharide (LPS)-induced acute lung injury via induction of AMPK/GSK3β-Nrf2 signal axis
H Lv, Q Liu, Z Wen, H Feng, X Deng, X Ci - Redox biology, 2017 - Elsevier
Abundant natural flavonoids can induce nuclear factor-erythroid 2 related factor 2 (Nrf2)
and/or AMP-activated protein kinase (AMPK) activation, which play crucial roles in the …
and/or AMP-activated protein kinase (AMPK) activation, which play crucial roles in the …
[HTML][HTML] Isovitexin exerts anti-inflammatory and anti-oxidant activities on lipopolysaccharide-induced acute lung injury by inhibiting MAPK and NF-κB and activating …
H Lv, Z Yu, Y Zheng, L Wang, X Qin… - International journal of …, 2016 - ncbi.nlm.nih.gov
Oxidative damage and inflammation are closely associated with the pathogenesis of acute
lung injury (ALI). Thus, we explored the protective effect of isovitexin (IV), a …
lung injury (ALI). Thus, we explored the protective effect of isovitexin (IV), a …
[HTML][HTML] The antityrosinase and antioxidant activities of flavonoids dominated by the number and location of phenolic hydroxyl groups
AR Zuo, HH Dong, YY Yu, QL Shu, LX Zheng, XY Yu… - Chinese medicine, 2018 - Springer
Background Compounds with the ability to scavenge reactive oxygen species (ROS) and
inhibit tyrosinase may be useful for the treatment and prevention from ROS-related diseases …
inhibit tyrosinase may be useful for the treatment and prevention from ROS-related diseases …
The protective effect of Trillin LPS-induced acute lung injury by the regulations of inflammation and oxidative state
W Jiang, F Luo, Q Lu, J Liu, P Li, X Wang, Y Fu… - Chemico-biological …, 2016 - Elsevier
Inflammation response and oxidative stress have been reported to be involved in the
pathogenesis of acute lung injury (ALI). Accordingly, anti-inflammatory treatment is proposed …
pathogenesis of acute lung injury (ALI). Accordingly, anti-inflammatory treatment is proposed …
Nrf2 as regulator of innate immunity: A molecular Swiss army knife!
M Battino, F Giampieri, F Pistollato, A Sureda… - Biotechnology …, 2018 - Elsevier
Organisms are constantly exposed to a broad range of pathological and stress-inducing
agents, allergens and environmental chemicals that can induce infections, toxicity or other …
agents, allergens and environmental chemicals that can induce infections, toxicity or other …
Flavonoids as potential phytotherapeutics to combat cytokine storm in SARS‐CoV‐2
Emergence of severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) infection,
COVID‐19, has become the global panic since December 2019, which urges the global …
COVID‐19, has become the global panic since December 2019, which urges the global …
Proinflammatory pathways: the modulation by flavonoids
Inflammation is a natural, carefully orchestrated response of the organism to tissue damage,
involving various signaling systems and the recruitment of inflammatory cells. These cells …
involving various signaling systems and the recruitment of inflammatory cells. These cells …
[HTML][HTML] Baicalein, a bioflavonoid, prevents cisplatin-induced acute kidney injury by up-regulating antioxidant defenses and down-regulating the MAPKs and NF-κB …
Acute renal failure is a serious complication of the anticancer drug cisplatin. The potential
role of baicalein, a naturally occurring bioflavonoid on cisplatin-induced renal injury is …
role of baicalein, a naturally occurring bioflavonoid on cisplatin-induced renal injury is …