In the last decade, organoid technology has become a cornerstone in cancer research.
Organoids are long-term primary cell cultures, usually of epithelial origin, grown in a three …

Gastric cancer (GC) is one of the most frequent and lethal malignancies in the world.
However, our understanding of the mechanisms underlying its initiation and progression is …

Chronic hepatitis B virus (HBV) infection, which threatens global public health, is a major
contributor to liver-related morbidity and mortality. Examinations for liver diseases related to …

Organoids are three-dimensional, multicellular constructs that recapitulate the structural and
functional features of specific organs. Because of these characteristics, organoids have …

Somatic copy number gains are pervasive across cancer types, yet their roles in
oncogenesis are insufficiently evaluated. This inadequacy is partly due to copy gains …

Chronic infection with hepatitis B virus (HBV) remains a global health concern despite the
availability of vaccines. To date, the development of effective treatments has been severely …

Organoid culture is an emerging research tool that has proved tremendously useful in a
multitude of aspects, one of which is cancer research. They largely overcome the limitations …

Simple Summary Pituitary adenoma pathophysiology has been studied mainly using murine
cell lines, animal models, and pituitary tumor samples. However, the lack of human pituitary …

Both cholangiocarcinoma (CCA) and gallbladder carcinoma (GBC) are belong to biliary tract
carcinomas (BTCs) with a high degree of malignancy and a poor prognosis. Therefore, an in …

Liver cancer is the second most lethal malignancy worldwide. Cell lines and murine models
are the most common tools for modeling human liver carcinogenesis. Most recently …