Gamma-aminobutyric acid Signaling in damage response, metabolism, and disease
K Kim, H Yoon - International Journal of Molecular Sciences, 2023 - mdpi.com
Gamma-aminobutyric acid (GABA) plays a crucial role in signal transduction and can
function as a neurotransmitter. Although many studies have been conducted on GABA in …
function as a neurotransmitter. Although many studies have been conducted on GABA in …
pH Auto-Sustain-Based Fermentation Supports Efficient Gamma-Aminobutyric Acid Production by Lactobacillus brevis CD0817
M Jia, Y Zhu, L Wang, T Sun, H Pan, H Li - Fermentation, 2022 - mdpi.com
Gamma-aminobutyric acid (GABA) plays a role in several physiological functions. GABA
production by lactic acid bacteria has attracted considerable interest; however, there is need …
production by lactic acid bacteria has attracted considerable interest; however, there is need …
FTY720 attenuates APAP‑induced liver injury via the JAK2/STAT3 signaling pathway
X He, K Kang, D Pan, Y Sun… - … Journal of Molecular …, 2022 - spandidos-publications.com
As the current clinical treatment of acetaminophen (APAP)‑induced liver injury (AILI) has its
limitations, new and effective treatment methods are required. Fingolimod (FTY720) is an …
limitations, new and effective treatment methods are required. Fingolimod (FTY720) is an …
Sodium-Ion-Free Fermentative Production of GABA with Levilactobacillus brevis CD0817
H Li, J Pei, C Wei, Z Lin, H Pan, Z Pan, X Guo, Z Yu - Metabolites, 2023 - mdpi.com
Gamma-aminobutyric acid (GABA) has positive effects on many physiological processes.
Lactic acid bacterial production of GABA is a future trend. This study aimed to produce a …
Lactic acid bacterial production of GABA is a future trend. This study aimed to produce a …
[HTML][HTML] Effects of ammonia toxicity on the histopathology, detoxification, oxidative stress, and immune response of the cuttlefish Sepia pharaonis and the mitigation of …
Y Liang, Y Wu, J Li, R Peng, M Jiang, X Jiang… - Ecotoxicology and …, 2022 - Elsevier
In this study, γ-aminobutyric acid (GABA) was examined as an additional supplement to
improve the ammonia stress resistance of S. pharaonis. Specifically, we added different …
improve the ammonia stress resistance of S. pharaonis. Specifically, we added different …
[HTML][HTML] Revealing the hypoglycemic effects and mechanism of GABA-rich germinated Adzuki beans on T2DM mice by untargeted serum metabolomics
X Jiang, Q Xu, A Zhang, Y Liu, Z Li, H Tang… - Frontiers in …, 2021 - frontiersin.org
Type 2 diabetes mellitus (T2DM) is one of the most common metabolic disease, exploring
the strategies of preventing and treating diabetes are extremely importan. Therefore, looking …
the strategies of preventing and treating diabetes are extremely importan. Therefore, looking …
An integrated systems-level model of ochratoxin A toxicity in the zebrafish (Danio rerio) embryo based on NMR metabolic profiling
MNH Eeza, N Bashirova, Z Zuberi, J Matysik… - Scientific Reports, 2022 - nature.com
Ochratoxin A (OTA) is one of the most widespread mycotoxin contaminants of agricultural
crops. Despite being associated with a range of adverse health effects, a comprehensive …
crops. Despite being associated with a range of adverse health effects, a comprehensive …
Opisthorchis viverrini Infection Induces Metabolic and Fecal Microbial Disturbances in Association with Liver and Kidney Pathologies in Hamsters
Opisthorchis viverrini (Ov) infection causes hepatobiliary diseases and is a major risk factor
for cholangiocarcinoma. While several omics approaches have been employed to …
for cholangiocarcinoma. While several omics approaches have been employed to …
[HTML][HTML] Increased GABA signaling in liver macrophage promotes HBV replication in HBV-carrier mice
Y Chen, Z Yin, X Zhang, Y Zhao, T Liu, WY Lu, S Wang - Virus Research, 2024 - Elsevier
Gamma-aminobutyric acid (GABA) signals in various non-neuronal cells including
hepatocytes and some immune cells. Studies, including ours, show that type A GABA …
hepatocytes and some immune cells. Studies, including ours, show that type A GABA …
Positive allosteric GABAA receptor modulation counteracts lipotoxicity-induced gene expression changes in hepatocytes in vitro
E Rohbeck, C Niersmann, K Köhrer… - Frontiers in …, 2023 - frontiersin.org
Introduction: We have previously shown that the novel positive allosteric modulator of the
GABAA receptor, HK4, exerts hepatoprotective effects against lipotoxicity-induced apoptosis …
GABAA receptor, HK4, exerts hepatoprotective effects against lipotoxicity-induced apoptosis …