[HTML][HTML] Coccidiosis: recent progress in host immunity and alternatives to antibiotic strategies

Y Lee, M Lu, HS Lillehoj - Vaccines, 2022 - mdpi.com
Coccidiosis is an avian intestinal disease caused by several distinct species of Eimeria
parasites that damage the host's intestinal system, resulting in poor nutrition absorption …

[HTML][HTML] Vaccines against chicken coccidiosis with particular reference to previous decade: progress, challenges, and opportunities

T Zaheer, RZ Abbas, M Imran, A Abbas, A Butt… - Parasitology …, 2022 - Springer
Chicken coccidiosis is an economically significant disease of commercial chicken industry
accounting for losses of more than£ 10.4 billion (according to 2016 prices). Additionally, the …

Live attenuated anticoccidial vaccines for chickens

Q Liu, X Liu, X Zhao, XQ Zhu, X Suo - Trends in Parasitology, 2023 - cell.com
Chicken coccidiosis, caused by infection with single or multiple Eimeria species, results in
significant economic losses to the global poultry industry. Over the past decades …

[HTML][HTML] A review of Eimeria antigen identification for the development of novel anticoccidial vaccines

J Venkatas, MA Adeleke - Parasitology research, 2019 - Springer
Coccidiosis is a major poultry disease which compromises animal welfare and costs the
global chicken industry a huge economic loss. As a result, research entailing coccidial …

[HTML][HTML] Designing multiepitope-based vaccine against Eimeria from immune mapped protein 1 (IMP-1) antigen using immunoinformatic approach

T Madlala, VT Adeleke, AJ Fatoba, M Okpeku… - Scientific Reports, 2021 - nature.com
Drug resistance against coccidiosis has posed a significant threat to chicken welfare and
productivity worldwide, putting daunting pressure on the poultry industry to reduce the use of …

[HTML][HTML] Efficient Single-Gene and Gene Family Editing in the Apicomplexan Parasite Eimeria tenella Using CRISPR-Cas9

D Hu, X Tang, C Ben Mamoun, C Wang… - … in Bioengineering and …, 2020 - frontiersin.org
Eimeria species are pathogenic protozoa with a wide range of hosts and the cause of poultry
coccidiosis, which results in huge economic losses to the poultry industry. These parasites …

[HTML][HTML] Adapted tissue assay for the assessment of ileal granulocyte degranulation following in ovo inoculation with select bacteria or coccidial challenge in chickens

AF Duff, KM Chasser, KE McGovern, M Trombetta… - Plos one, 2023 - journals.plos.org
A previously described heterophil degranulation assay was adapted for use with ileal
mucosal tissue via quantification of β-D-glucuronidase and assay end product 4 …

[HTML][HTML] Evidence of high-efficiency cross fertilization in Eimeria acervulina revealed using two lines of transgenic parasites

J Liu, F Shi, Y Zhang, X Tang, C Wang, Y Gao… - International Journal for …, 2023 - Elsevier
Eimeria species are apicomplexan parasites with a direct life cycle consisting of a replicative
phase involving multiple rounds of asexual replication in the intestine or other organs …

Transgenic Eimeria parasite: A potential control strategy for chicken coccidiosis

AJ Fatoba, MA Adeleke - Acta tropica, 2020 - Elsevier
Poultry industry has been very instrumental in curtailing malnutrition and poverty and as
such contributing to economic growth. However, production loss in poultry industry due to …

[HTML][HTML] Co-immunization with two recombinant Eimeria tenella lines expressing immunoprotective antigens of E. maxima elicits enhanced protection against E …

X Tang, C Wang, L Liang, D Hu, S Zhang, C Duan… - Parasites & vectors, 2019 - Springer
Background Live anticoccidial vaccines have been a tremendous success for disease
prevention. The establishment of the reverse genetic manipulation platform has enabled the …