Antiviral drugs for cytomegalovirus diseases
KK Biron - Antiviral research, 2006 - Elsevier
Cytomegalovirus infections are associated with severe morbidity and mortality is patients at
risk for disease because of immune system disabilities; in particular, recipients of stem cell …
risk for disease because of immune system disabilities; in particular, recipients of stem cell …
[HTML][HTML] Cytomegalovirus infection after liver transplantation: current concepts and challenges
RR Razonable - World journal of gastroenterology: WJG, 2008 - ncbi.nlm.nih.gov
Cytomegalovirus (CMV) is a common viral pathogen that influences the outcome of liver
transplantation. In addition to the direct effects of CMV syndrome and tissue-invasive …
transplantation. In addition to the direct effects of CMV syndrome and tissue-invasive …
[HTML][HTML] Cell-mediated immunity to predict cytomegalovirus disease in high-risk solid organ transplant recipients
D Kumar, S Chernenko, G Moussa, I Cobas… - American journal of …, 2009 - Elsevier
Late-onset cytomegalovirus (CMV) disease commonly occurs after discontinuation of
antiviral prophylaxis. We determined the utility of testing CD8+ T-cell response against CMV …
antiviral prophylaxis. We determined the utility of testing CD8+ T-cell response against CMV …
[HTML][HTML] Improvement in long-term renal graft survival due to CMV prophylaxis with oral ganciclovir: results of a randomized clinical trial
V Kliem, L Fricke, T Wollbrink, M Burg… - American Journal of …, 2008 - Elsevier
Oral ganciclovir prophylaxis and intravenous preemptive therapy are competitive
approaches to prevent cytomegalovirus (CMV) disease after renal transplantation. This trial …
approaches to prevent cytomegalovirus (CMV) disease after renal transplantation. This trial …
High risk of cytomegalovirus infection following solid organ transplantation despite prophylactic therapy
H Harvala, C Stewart, K Muller, S Burns… - Journal of medical …, 2013 - Wiley Online Library
Cytomegalovirus infection (CMV) in solid organ transplant recipients is a major clinical
problem. The aim of this study was to evaluate the incidence of CMV infection and its …
problem. The aim of this study was to evaluate the incidence of CMV infection and its …
Cytomegalovirus pneumonitis is a risk for bronchiolitis obliterans syndrome in lung transplantation
LD Snyder, CA Finlen-Copeland… - American journal of …, 2010 - atsjournals.org
Rationale: Cytomegalovirus pneumonitis is one of the most prevalent opportunistic
infections after lung transplantation. Early studies reported that cytomegalovirus pneumonitis …
infections after lung transplantation. Early studies reported that cytomegalovirus pneumonitis …
Phase 2 randomized, double-blind, placebo-controlled trial of RG7667, a combination monoclonal antibody, for prevention of cytomegalovirus infection in high-risk …
JH Ishida, A Patel, AK Mehta, P Gatault… - Antimicrobial agents …, 2017 - Am Soc Microbiol
Cytomegalovirus (CMV) infection is a significant complication after kidney transplantation.
We examined the ability of RG7667, a combination of two monoclonal antibodies, to prevent …
We examined the ability of RG7667, a combination of two monoclonal antibodies, to prevent …
Structural basis for potent antibody-mediated neutralization of human cytomegalovirus
S Chandramouli, E Malito, TV Nguyen, K Luisi… - Science …, 2017 - science.org
Human cytomegalovirus (HCMV) is the leading viral cause of birth defects and organ
transplant rejection. The HCMV gH/gL/UL128/UL130/UL131A complex (Pentamer) is the …
transplant rejection. The HCMV gH/gL/UL128/UL130/UL131A complex (Pentamer) is the …
Antiviral treatment of cytomegalovirus infection
A Ahmed - Infectious Disorders-Drug Targets (Formerly Current …, 2011 - ingentaconnect.com
Cytomegalovirus (CMV) is an opportunistic pathogen associated with significant morbidity
and mortality in immunocompromised hosts. Antiviral agents specifically targeting CMV were …
and mortality in immunocompromised hosts. Antiviral agents specifically targeting CMV were …
[HTML][HTML] Prevention of posttransplant cytomegalovirus disease and related outcomes with valganciclovir: a systematic review
HY Sun, MM Wagener, N Singh - American Journal of Transplantation, 2008 - Elsevier
The precise impact of valganciclovir as preventive therapy for cytomegalovirus (CMV) in
solid organ transplant (SOT) recipients is not fully defined. Data from studies using …
solid organ transplant (SOT) recipients is not fully defined. Data from studies using …