Phase 1 randomized, double-blind, placebo-controlled study of RG7667, an anticytomegalovirus combination monoclonal antibody therapy, in healthy adults

JH Ishida, T Burgess, MA Derby… - Antimicrobial Agents …, 2015 - Am Soc Microbiol
Cytomegalovirus can cause debilitating and life-threatening disease in newborns infected in
utero and immunocompromised individuals, including transplant recipients. RG7667 is a …

The risk, prevention, and outcome of cytomegalovirus after pediatric lung transplantation

LA Danziger-Isakov, S Worley, MG Michaels… - …, 2009 - journals.lww.com
Background. A retrospective review of pediatric lung transplant recipients at 14 centers in
North America and Europe was conducted to characterize the epidemiology and the risk …

Indirect effects of cytomegalovirus infection in solid organ transplant recipients

MJ Pérez-Sola, JJ Castón, R Solana, A Rivero… - … y microbiologia clinica, 2008 - Elsevier
Cytomegalovirus (CMV) infection is an important and frequent complication in solid organ
transplant (SOT) recipients. This infection causes direct effects by viral inclusion in the cells …

[HTML][HTML] Is prevention the best treatment? CMV after lung transplantation

N Patel, LD Snyder, CAF Copeland… - American Journal of …, 2012 - Elsevier
Cytomegalovirus (CMV) is the most prevalent opportunistic infection that occurs in lung-
transplant recipients. In addition to its direct morbidity, multiple studies have demonstrated …

Association between a polymorphism in the human programmed death-1 (PD-1) gene and cytomegalovirus infection after kidney transplantation

TW Hoffmann, JM Halimi, M Büchler… - Journal of medical …, 2010 - jmg.bmj.com
Background Cytomegalovirus (CMV) infection is the most frequent infectious disease
following organ transplantation. Strategies to prevent this infection remain a matter for …

Maternal Antibody Responses and Nonprimary Congenital Cytomegalovirus Infection of HIV-1–Exposed Infants

KM Bialas, D Westreich… - The Journal of …, 2016 - academic.oup.com
Risk of congenital cytomegalovirus (cCMV) transmission is highly dependent on the
presence of preexisting maternal immunity, with the lowest rates observed in CMV …

Decreased incidence of cytomegalovirus infection with sirolimus in a post hoc randomized, multicenter study in lung transplantation

B Ghassemieh, VN Ahya, MA Baz, VG Valentine… - The Journal of Heart and …, 2013 - Elsevier
BACKGROUND: Cytomegalovirus (CMV) is the most common opportunistic infection in lung
transplantation. A recent multicenter, randomized trial (the AIRSAC study) comparing …

Virus load dynamics of individual CMV‐genotypes in lung transplant recipients with mixed‐genotype infections

I Görzer, H Kerschner, P Jaksch, C Bauer… - Journal of medical …, 2008 - Wiley Online Library
Human cytomegalovirus (CMV) is a major cause of disease and transplant dysfunction in
lung transplant recipients. Simultaneous emergence of more than one CMV‐genotype can …

Prevention strategies for cytomegalovirus disease and long‐term outcomes in the high‐risk transplant patient (D+/R−): experience from the RESITRA‐REIPI cohort

Y Meije, J Fortún, O Len, JM Aguado… - Transplant Infectious …, 2014 - Wiley Online Library
Background Cytomegalovirus (CMV)‐negative recipients of a graft from a CMV‐positive
donor (D+/R−) are at high risk of CMV disease. Current preventive strategies include …

From recognition to execution—The HCMV Pentamer from receptor binding to fusion triggering

E Malito, S Chandramouli, A Carfi - Current opinion in virology, 2018 - Elsevier
The β-herpesvirus human cytomegalovirus (HCMV) is the leading viral cause of neonatal
developmental disabilities. In HCMV, the conserved herpesvirus glycoprotein B (gB) …