Alzheimer's disease: an update and insights into pathophysiology
Alzheimer's disease (AD) is an irreversible brain disorder associated with slow, progressive
loss of brain functions mostly in older people. The disease processes start years before the …
loss of brain functions mostly in older people. The disease processes start years before the …
Antibiotics and mental health: The good, the bad and the ugly
K Dinan, T Dinan - Journal of Internal Medicine, 2022 - Wiley Online Library
Antibiotics are recognised as, on occasion, producing psychiatric side effects, most notably
depression and anxiety. Apart from antimicrobial activity, antibiotics have multiple off‐target …
depression and anxiety. Apart from antimicrobial activity, antibiotics have multiple off‐target …
Minocycline promotes functional recovery in ischemic stroke by modulating microglia polarization through STAT1/STAT6 pathways
Y Lu, M Zhou, Y Li, Y Li, Y Hua, Y Fan - Biochemical pharmacology, 2021 - Elsevier
Background Increasing evidence suggests that microglia experience two distinct
phenotypes after acute ischemic stroke (AIS): a deleterious M1 phenotype and a …
phenotypes after acute ischemic stroke (AIS): a deleterious M1 phenotype and a …
Inherited retinal dystrophies: role of oxidative stress and inflammation in their physiopathology and therapeutic implications
I Pinilla, V Maneu, L Campello, L Fernández-Sánchez… - Antioxidants, 2022 - mdpi.com
Inherited retinal dystrophies (IRDs) are a large group of genetically and clinically
heterogeneous diseases characterized by the progressive degeneration of the retina …
heterogeneous diseases characterized by the progressive degeneration of the retina …
Breaking down the cellular responses to type I interferon neurotoxicity in the brain
B Viengkhou, MJ Hofer - Frontiers in Immunology, 2023 - frontiersin.org
Since their original discovery, type I interferons (IFN-Is) have been closely associated with
antiviral immune responses. However, their biological functions go far beyond this role, with …
antiviral immune responses. However, their biological functions go far beyond this role, with …
[PDF][PDF] 红细胞血型抗原的最新研究进展
张黎雯, 李树中, 田丰, 李凌波, 李中华 - 临床血液学杂志, 2021 - lcxyen.whuhzzs.com
Abstract InOctober2019, ISBTpublished39RBCbloodgroupsystemsa…. Sofar, 391RBCbloodgroupantigenshavebeeniden…
, ofwhich367havebeenidentifiedas" system"," collection" and" series" antigensbyISBT, and24havenotbeenidentifiedandclassifiedb …
, ofwhich367havebeenidentifiedas" system"," collection" and" series" antigensbyISBT, and24havenotbeenidentifiedandclassifiedb …
The microbiota–gut–brain axis in Huntington's disease: pathogenic mechanisms and therapeutic targets
Huntington's disease (HD) is a currently incurable neurogenerative disorder and is typically
characterized by progressive movement disorder (including chorea), cognitive deficits …
characterized by progressive movement disorder (including chorea), cognitive deficits …
The medicinal chemistry of Urtica dioica L.: from preliminary evidence to clinical studies supporting its neuroprotective activity
Urtica dioica is a perennial herb from the family of Urticaceae that is commonly known as
stinging nettle. This plant is widespread in Europe, Africa, America, and a part of Asia, as it …
stinging nettle. This plant is widespread in Europe, Africa, America, and a part of Asia, as it …
Tetracyclines—an important therapeutic tool for dermatologists
M Orylska-Ratynska, W Placek… - International Journal of …, 2022 - mdpi.com
Tetracyclines are a group of antibiotics whose first representative was discovered over 70
years ago. Since then, they have been of great interest in dermatology. In addition to their …
years ago. Since then, they have been of great interest in dermatology. In addition to their …
Minocycline attenuates cholinergic dysfunction and neuro-inflammation-mediated cognitive impairment in scopolamine-induced Alzheimer's rat model
S Amirahmadi, FD Farimani, M Akbarian, F Mirzavi… - …, 2022 - Springer
Objective Minocycline, a semisynthetic tetracycline-derived antibiotic, has various
pharmacological effect such as anti-inflammatory, anti-oxidative stress, and anti-apoptotic …
pharmacological effect such as anti-inflammatory, anti-oxidative stress, and anti-apoptotic …