Alzheimer's disease: an update and insights into pathophysiology

MB Abubakar, KO Sanusi, A Ugusman… - Frontiers in aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is an irreversible brain disorder associated with slow, progressive
loss of brain functions mostly in older people. The disease processes start years before the …

Antibiotics and mental health: The good, the bad and the ugly

K Dinan, T Dinan - Journal of Internal Medicine, 2022 - Wiley Online Library
Antibiotics are recognised as, on occasion, producing psychiatric side effects, most notably
depression and anxiety. Apart from antimicrobial activity, antibiotics have multiple off‐target …

Minocycline promotes functional recovery in ischemic stroke by modulating microglia polarization through STAT1/STAT6 pathways

Y Lu, M Zhou, Y Li, Y Li, Y Hua, Y Fan - Biochemical pharmacology, 2021 - Elsevier
Background Increasing evidence suggests that microglia experience two distinct
phenotypes after acute ischemic stroke (AIS): a deleterious M1 phenotype and a …

Inherited retinal dystrophies: role of oxidative stress and inflammation in their physiopathology and therapeutic implications

I Pinilla, V Maneu, L Campello, L Fernández-Sánchez… - Antioxidants, 2022 - mdpi.com
Inherited retinal dystrophies (IRDs) are a large group of genetically and clinically
heterogeneous diseases characterized by the progressive degeneration of the retina …

Breaking down the cellular responses to type I interferon neurotoxicity in the brain

B Viengkhou, MJ Hofer - Frontiers in Immunology, 2023 - frontiersin.org
Since their original discovery, type I interferons (IFN-Is) have been closely associated with
antiviral immune responses. However, their biological functions go far beyond this role, with …

[PDF][PDF] 红细胞血型抗原的最新研究进展

张黎雯, 李树中, 田丰, 李凌波, 李中华 - 临床血液学杂志, 2021 - lcxyen.whuhzzs.com
Abstract InOctober2019, ISBTpublished39RBCbloodgroupsystemsa…. Sofar, 391RBCbloodgroupantigenshavebeeniden…
, ofwhich367havebeenidentifiedas" system"," collection" and" series" antigensbyISBT, and24havenotbeenidentifiedandclassifiedb …

The microbiota–gut–brain axis in Huntington's disease: pathogenic mechanisms and therapeutic targets

MN Ekwudo, C Gubert, AJ Hannan - The FEBS Journal, 2024 - Wiley Online Library
Huntington's disease (HD) is a currently incurable neurogenerative disorder and is typically
characterized by progressive movement disorder (including chorea), cognitive deficits …

The medicinal chemistry of Urtica dioica L.: from preliminary evidence to clinical studies supporting its neuroprotective activity

P Semwal, A Rauf, A Olatunde, P Singh… - Natural products and …, 2023 - Springer
Urtica dioica is a perennial herb from the family of Urticaceae that is commonly known as
stinging nettle. This plant is widespread in Europe, Africa, America, and a part of Asia, as it …

Tetracyclines—an important therapeutic tool for dermatologists

M Orylska-Ratynska, W Placek… - International Journal of …, 2022 - mdpi.com
Tetracyclines are a group of antibiotics whose first representative was discovered over 70
years ago. Since then, they have been of great interest in dermatology. In addition to their …

Minocycline attenuates cholinergic dysfunction and neuro-inflammation-mediated cognitive impairment in scopolamine-induced Alzheimer's rat model

S Amirahmadi, FD Farimani, M Akbarian, F Mirzavi… - …, 2022 - Springer
Objective Minocycline, a semisynthetic tetracycline-derived antibiotic, has various
pharmacological effect such as anti-inflammatory, anti-oxidative stress, and anti-apoptotic …