The relative contribution of founder effects and natural selection to the observed distribution
of human blood groups has been debated since blood group frequencies were shown to …

Red blood cell (RBC) blood group antigens are polymorphic, inherited, carbohydrate or
protein structures located on the extracellular surface of the RBC membrane. They …

Blood group variants are characteristic of population groups, and can show conspicuous
geographic patterns. Interest in the global prevalence of the Duffy blood group variants is …

Malaria therapy, experimental, and epidemiological studies have shown that erythrocyte
Duffy blood group-negative people, largely of African ancestry, are resistant to erythrocyte …

The Duffy blood group locus, which encodes a chemokine receptor, is characterized by
three alleles—FY* A, FY* B, and FY* O. The frequency of the FY* O allele, which …

The erythrocyte silent Duffy blood group phenotype in Africans is thought to confer
resistance to Plasmodium vivax blood-stage infection. However, recent studies report P …

Resistance to Plasmodium vivax blood-stage infection has been widely recognised to result
from absence of the Duffy (Fy) blood group from the surface of red blood cells (RBCs) in …

ACKR1, located on chromosome 1q23. 2, is the gene that encodes a glycoprotein
expressing the Duffy blood group antigens. This gene is transcribed in two mRNA variants …

Background Duffy blood group polymorphisms are important in areas where Plasmodium
vivax is present because this surface antigen is thought to act as a key receptor for this …

Rhesus (Rh) antigens are defined by a complex association of membrane polypeptides that
are missing or severely deficient from the red cells of rare Rhnullindividuals who suffer a …