Skeletal muscle contains a designated population of adult stem cells, called satellite cells,
which are generally quiescent. In homeostasis, satellite cells proliferate only sporadically …

Emerging insights into cellular senescence highlight the relevance of senescence in
musculoskeletal disorders, which represent the leading global cause of disability. Cellular …

Stem cells play central roles in tissue development, homeostasis, and regeneration.
Decades of scientific research have uncovered processes of stem cell decline in tissue and …

Muscle stem cells (MuSCs) reside in a specialized niche that ensures their regenerative
capacity. Although we know that innate immune cells infiltrate the niche in response to …

The phenotypic heterogeneity and functional diversity of macrophages confer on them
complexed roles in the development and progression of kidney diseases. After kidney injury …

Stem cell niches are composed of dynamic microenvironments that support stem cells over a
lifetime. The emerging niche is distinct from the adult because its main role is to support the …

Scaffold is one of the most important roles in skeletal muscle tissue engineering. Being
capable of mimicking extracellular matrix components, having electrical conductivity, and …

Satellite cells support adult skeletal muscle fiber adaptations to loading in numerous ways.
The fusion of satellite cells, driven by cell‐autonomous and/or extrinsic factors, contributes …

Tissue-specific stem cells persist for a lifetime and can differentiate to maintain homeostasis
or transform to initiate cancer. Despite their importance, there are no described quality …

Skeletal muscle stem and progenitor cells including those derived from human pluripotent
stem cells (hPSCs) offer an avenue towards personalized therapies and readily fuse to form …