Castration-resistant prostate cancer (CRPC), especially metastatic castration-resistant
prostate cancer (mCRPC) is one of the most prevalent malignancies and main cause of …

Plants have an extraordinary diversity of transcription machineries, including five nuclear
DNA-dependent RNA polymerases. Four of these enzymes are dedicated to the production …

With the advent of next generation sequencing methods and progress in transcriptome
analysis, it became obvious that the human genome contains much more than just protein …

Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm
demonstrating potential roles in both oncogenic and tumor suppressive pathways. These …

The human genome contains many thousands of long noncoding RNAs (lncRNAs). While
several studies have demonstrated compelling biological and disease roles for individual …

The present review aimed to outline different types of RNAs in cancer diagnostics and
treatment, and to provide novel insights into their clinical applications. RNAs, including …

In the past century, nearly all of the biological sciences have been directly affected by
discoveries and developments in genetics, a fast-evolving subject with important theoretical …

Glioblastoma (GBM) is the most common and aggressive primary brain tumor. Great interest
persists in useful therapeutic targets in GBM. Aberrant expression of long non-coding RNAs …

Noncoding RNAs (ncRNAs) include a diverse range of RNA species, including microRNAs
(miRNAs) and long noncoding RNAs (lncRNAs). MiRNAs, ncRNAs of approximately 19–25 …

Data from the Encyclopedia of DNA Elements (ENCODE) project show over 9640 human
genome loci classified as long noncoding RNAs (lncRNAs), yet only∼ 100 have been …