The recent progress in biomaterials science and development of tubular conduits (TCs) still
fails in solving the current challenges in the treatment of peripheral nerve injuries (PNIs), in …

The blood–brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB) represent
two complex structures protecting the central nervous system (CNS) against potentially …

The meninges surround the brain and spinal cord, affording physical protection while also
serving as a niche of neuroimmune activity. Though possessing stromal qualities, its …

Experimental autoimmune encephalomyelitis is a CD4+ T cell–mediated demyelinating
disease of the CNS that serves as a model for multiple sclerosis. Cytokines and chemokines …

Oligodendrocytes and their progenitors upregulate MHC pathways in response to
inflammation, but the frequency of this phenotypic change is unknown and the features of …

Microglia are important for central nervous system (CNS) homeostasis and first to respond to
tissue damage and perturbations. Microglia are heterogeneous cells; in case of pathology …

We aimed to determine the effect of soluble epoxide hydrolase (sEH) inhibition on chronic
experimental autoimmune encephalomyelitis (EAE), a murine model of multiple sclerosis …

Olfactory dysfunction is deeply associated with quality of human life in the aging population.
Olfactory dysfunction is an occasional presymptomatic sign of neuroimmunological multiple …

The brain ventricles are part of the fluid compartments bridging the CNS with the periphery.
Using MRI, we previously observed a pronounced increase in ventricle volume (VV) in the …

Background Leptomeningeal inflammation, as evidenced by leptomeningeal contrast
enhancement (LMCE), is associated to cortical pathology in multiple sclerosis. The temporal …