Factors affecting the GABAergic synapse function in Alzheimer's disease: Focus on microRNAs

J Rivera, B Sharma, MM Torres, S Kumar - Ageing Research Reviews, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurological disease characterized by the loss of
cognitive function, confusion, and memory deficit. Accumulation of abnormal proteins …

[HTML][HTML] Recent trends and practices toward assessment and rehabilitation of neurodegenerative disorders: Insights from human gait

R Das, S Paul, GK Mourya, N Kumar… - Frontiers in …, 2022 - frontiersin.org
The study of human movement and biomechanics forms an integral part of various clinical
assessments and provides valuable information toward diagnosing neurodegenerative …

Current and emerging therapeutic targets of alzheimer's disease for the design of multi-target directed ligands

L Blaikie, G Kay, PKT Lin - MedChemComm, 2019 - pubs.rsc.org
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease, and a major
cause of death worldwide. The number of people suffering from this debilitating disorder is …

[HTML][HTML] Mutual two-way interactions of curcumin and gut microbiota

R Pluta, S Januszewski, M Ułamek-Kozioł - International journal of …, 2020 - mdpi.com
Curcumin, an herbal naturally occurring polyphenol, has recently been proposed for the
treatment of neurodegenerative, neurological and cancer diseases due to its pleiotropic …

[HTML][HTML] Unlocking the Therapeutic Potential of Medicinal Plants for Alzheimer's Disease: Preclinical to Clinical Trial Insights

K Nagori, KT Nakhate, K Yadav, Ajazuddin… - Future …, 2023 - mdpi.com
Alzheimer's disease (AD) is a progressive, multifactorial, and unremitting neurodegenerative
disease characterized by memory loss, personality changes, and cognitive impairment. It …

[HTML][HTML] Dietary protection against cognitive impairment, Neuroinflammation and oxidative stress in Alzheimer's disease animal models of lipopolysaccharide-induced …

D Decandia, F Gelfo, E Landolfo, F Balsamo… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a rapidly growing epidemic with a heavy social and economic
burden. Evidence suggests that systemic inflammation, dysregulation of the immune …

Role of microbial dysbiosis in the pathogenesis of Alzheimer's disease

G Susmitha, R Kumar - Neuropharmacology, 2023 - Elsevier
Alzheimer's disease (AD) is the leading cause of dementia in the elderly and detected
during the advanced stages where the chances of reversal are minimum. The gut-brain axis …

The protective effects of curcumin on depression: genes, transcription factors, and microRNAs involved

HD Nguyen, MS Kim - Journal of affective disorders, 2022 - Elsevier
Background We aim to identify the molecular mechanisms for curcumin's anti-depressant
properties, including genes, transcription factors, and miRNAs. Methods The Comparative …

[HTML][HTML] The role of obesity and diabetes in dementia

A Selman, S Burns, AP Reddy, J Culberson… - International journal of …, 2022 - mdpi.com
Chronic conditions such as obesity, diabetes, and dementia are increasing in the United
States (US) population. Knowledge of these chronic conditions, preventative measures, and …

[HTML][HTML] Nature-derived compounds modulating Wnt/β-catenin pathway: a preventive and therapeutic opportunity in neoplastic diseases

G Sferrazza, M Corti, G Brusotti, P Pierimarchi… - … Pharmaceutica Sinica B, 2020 - Elsevier
The Wnt/β-catenin signaling is a conserved pathway that has a crucial role in embryonic and
adult life. Dysregulation of the Wnt/β-catenin pathway has been associated with diseases …