During acute or chronic lung injury, inappropriate immune response and/or aberrant repair
process causes irreversible damage in lung tissue and most usually results in the …

Rationale: There are no studies on withdrawal of inhaled corticosteroids in patients on long-
term triple therapy in the absence of frequent exacerbations. Objectives: To evaluate the …

Background Oxidative stress and persistent airway inflammation are thought to be important
contributors to the development of chronic obstructive pulmonary disease (COPD). This …

Inhaled corticosteroids (ICS) combined with bronchodilators can reduce the frequency of
exacerbations in some patients with chronic obstructive pulmonary disease (COPD). There …

Evidence and guidelines are becoming increasingly clear about imbalance between the
risks and benefits of inhaled corticosteroids (ICSs) in patients with COPD. While selected …

Observational studies indicate that overutilization of inhaled corticosteroids (ICS) is common
in patients with chronic obstructive pulmonary disease (COPD). Overprescription and the …

Background Recent data from real world clinical practices on the use of Triple Therapy (TT)
in patients with COPD are scarce. Methods Observational population-based study with …

Background Inhaled corticosteroids (ICS) are indicated for prevention of exacerbations in
patients with COPD, but they are frequently overprescribed. ICS withdrawal has been …

RATIONALE: There are no studies on ICS withdrawal in patients on long-term triple therapy
in the absence of frequent exacerbations. OBJECTIVE: To evaluate the efficacy and safety of …

Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and
mortality, with exacerbations contributing strongly to the overall severity and burden of …