Non‐alcoholic fatty liver disease (NAFLD) encompasses a spectrum of liver diseases, of
which the first stage is steatosis. It is one of the most common liver diseases in developed …

High concentrations of nonesterified fatty acids (NEFAs) and β‐hydroxybutyric acid (BHBA)
induce lipid peroxidation, resulting in liver damage. Choline and methionine (Met) can …

Objective—The mechanisms underlying the cardiovascular benefit of the anti-diabetic drug
metformin are poorly understood. Recent studies have suggested metformin may upregulate …

The present study aimed to investigate the effect of metformin on the induction of autophagy
in the liver and adipose tissues of a mouse model of obesity. C57BL/6J mice were fed a high …

Vascular calcification increases the risk of developing cardiovascular disease, and it is
closely associated with metabolic disorders such as diabetes mellitus and non-alcoholic …

There is increasing evidence that alcohol-induced white adipose tissue (WAT) dysfunction
contributes to disturbance of hepatic lipid metabolism. This study investigated the effects of …

Abstract Etnopharmacological relevance Eucalyptus tereticornis Sm.(Eu) is a plant species
used in traditional medicine to treat diabetes mellitus. Eu leaf extracts have been shown to …

Indole is a microbiota metabolite that functions to protect against obesity-associated non-
alcoholic fatty liver disease. The present study examined the extent to which indole …

Metformin has been used for the treatment of type II diabetes mellitus for decades due to its
safety, low cost, and outstanding hypoglycemic effect clinically. The mechanisms underlying …

Obesity-associated insulin resistance is a major risk factor for most metabolic diseases,
including dyslipidemia and type 2 diabetes. Acanthopanax senticosus (Rupr. et Maxim.) …