Role of Nrf2, STAT3, and Src as molecular targets for cancer chemoprevention
Cancer is a complex and multistage disease that affects various intracellular pathways,
leading to rapid cell proliferation, angiogenesis, cell motility, and migration, supported by …
leading to rapid cell proliferation, angiogenesis, cell motility, and migration, supported by …
The dual and multifaceted role of relaxin-2 in cancer
LB Kwantwi - Clinical and Translational Oncology, 2023 - Springer
The continuous increase in cancer-associated deaths despite the substantial improvement
in diagnosis and treatment has sparked discussions on the need for novel biomarkers and …
in diagnosis and treatment has sparked discussions on the need for novel biomarkers and …
CRISPRi screens identify the lncRNA, LOUP, as a multifunctional locus regulating macrophage differentiation and inflammatory signaling
H Halasz, E Malekos, S Covarrubias… - Proceedings of the …, 2024 - National Acad Sciences
Long noncoding RNAs (lncRNAs) account for the largest portion of RNA from the
transcriptome, yet most of their functions remain unknown. Here, we performed two …
transcriptome, yet most of their functions remain unknown. Here, we performed two …
[HTML][HTML] A signature constructed with mitophagy-related genes to predict the prognosis and therapy response for breast cancer
Y Zhao, Y Zhang, C Dai, K Hong, Y Guo - Aging (Albany NY), 2022 - ncbi.nlm.nih.gov
Over the past decades, the incidence and mortality rates of breast cancer (BC) have
increased rapidly; however, molecular biomarkers that can reliably detect BC are yet to be …
increased rapidly; however, molecular biomarkers that can reliably detect BC are yet to be …
Potential chemopreventive role of pterostilbene in its modulation of the apoptosis pathway
Cancer incidence keeps increasing every year around the world and is one of the leading
causes of death worldwide. Cancer has imposed a major burden on the human population …
causes of death worldwide. Cancer has imposed a major burden on the human population …
Fucoidan's molecular targets: A comprehensive review of its unique and multiple targets accounting for promising bioactivities supported by in silico studies
Fucoidan is a class of multifunctional polysaccharides derived from marine organisms. Its
unique and diversified physicochemical and chemical properties have qualified them for …
unique and diversified physicochemical and chemical properties have qualified them for …
Transcriptomics-based investigation of molecular mechanisms underlying apoptosis induced by ZnO nanoparticles in human diffuse large B-cell lymphoma
SA Alsagaby - International Journal of Nanomedicine, 2022 - Taylor & Francis
Introduction Zinc oxide nanoparticles (ZnO NPs) show anti-cancer activity. Diffuse Large B-
cell Lymphoma (DLBCL) is a type of B-cell malignancies with unsatisfying treatment …
cell Lymphoma (DLBCL) is a type of B-cell malignancies with unsatisfying treatment …
Curcumin potentiates the anti-inflammatory effects of Tehranolide by modulating the STAT3/NF-κB signaling pathway in breast and ovarian cancer cell lines
Background Studies have demonstrated that natural products, such as curcumin and
artemisinin, possess anti-inflammatory effects, which can be beneficial for cancer treatment …
artemisinin, possess anti-inflammatory effects, which can be beneficial for cancer treatment …
Polyethyleneglycol-betulinic acid (PEG-BA) polymer-drug conjugate induces apoptosis and antioxidation in a biological model of pancreatic cancer
Pancreatic cancer (PC) is one of the most aggressive solid malignancies with poor treatment
response and low survival rates. Herbal medicines such as betulinic acid (BA) have shown …
response and low survival rates. Herbal medicines such as betulinic acid (BA) have shown …
Macrophage activation by exopolysaccharides from Streptococcus thermophilus fermented milk through TLRs-mediated NF-κB and MAPK pathways
W Xu, F Cao, M Zhao, X Fu, S Yin, Y Sun… - International …, 2022 - Elsevier
Lactic acid bacteria-derived exopolysaccharides are known for stimulating immune
responses. In our previous study, a novel exopolysaccharide (EPS-3A) from skimmed milk …
responses. In our previous study, a novel exopolysaccharide (EPS-3A) from skimmed milk …