The capacity of the 3D-organoid cultures to resemble a near-physiological tissue
organization and to mimic–to a certain degree–organ functionality, make organoids an …

The evolutionarily conserved default mode network (DMN) is a distributed set of brain
regions coactivated during resting states that is vulnerable to brain disorders. How disease …

Drug addiction is a worldwide societal problem and public health burden, and results from
recreational drug use that develops into a complex brain disorder. The opioid system, one of …

INTRODUCTION Motivational drives are internal states that can be different even in similar
interactions with external stimuli. Curiosity as the motivational drive for novelty-seeking and …

Visual perception and behavior are mediated by cortical areas that have been distinguished
using architectonic and retinotopic criteria. We employed fluorescence imaging and …

Optical manipulations of genetically defined cell types have generated significant insights
into the dynamics of neural circuits. While optogenetic activation has been relatively …

Abundant evidence supports the presence of at least three distinct types of thalamocortical
(TC) neurons in the primate dorsal lateral geniculate nucleus (dLGN) of the thalamus, the …

Fluorescent calcium indicators are often used to investigate neural dynamics, but the
relationship between fluorescence and action potentials (APs) remains unclear. Most APs …

The sense of touch is fundamental as it provides vital, moment-to-moment information about
the nature of our physical environment. Primary sensory neurons provide the basis for this …

INTRODUCTION Brain function is often compared to an orchestral ensemble, where
subgroups of neurons that have similar activity are analogous to different types of …