The therapeutic potential of carnosine as an antidote against drug-induced cardiotoxicity and neurotoxicity: Focus on nrf2 pathway

G Caruso, A Privitera, BM Antunes, G Lazzarino… - Molecules, 2022 - mdpi.com
Different drug classes such as antineoplastic drugs (anthracyclines, cyclophosphamide, 5-
fluorouracil, taxanes, tyrosine kinase inhibitors), antiretroviral drugs, antipsychotic, and …

Ameliorative effect of oregano (Origanum vulgare) versus silymarin in experimentally induced hepatic encephalopathy

EAR Abdelghffar, HAS El-Nashar, S Fayez… - Scientific Reports, 2022 - nature.com
Hepatic encephalopathy (HE) is a deterioration of brain function in patients suffering from
chronic liver disease, cirrhosis as a result of elevated blood ammonia and the production of …

Neuroprotective effect of tangeretin against chromium-induced acute brain injury in rats: targeting Nrf2 signaling pathway, inflammatory mediators, and apoptosis

AA Sedik, R Elgohary - Inflammopharmacology, 2023 - Springer
Potassium dichromate (PD) is an environmental xenobiotic commonly recognized as
teratogenic, carcinogenic, and mutagenic in animals and humans. The present study was …

Carvedilol attenuates brain damage in mice with hepatic encephalopathy

K Amirshahrokhi, A Niapour - International Immunopharmacology, 2022 - Elsevier
Brain injury is the most common and serious consequence of hepatic encephalopathy (HE),
and its pathophysiology is poorly understood. Excessive inflammatory, oxidative and …

Thioacetamide-induced acute hepatic encephalopathy: central vs peripheral effect of Allicin

DO Saleh, DF Mansour, AM Fayez - Metabolic Brain Disease, 2021 - Springer
Hepatic encephalopathy (HE) is a debilitating and life-threatening disease. Results from
acute or chronic liver failure and is characterized by abnormal cerebral and neurological …

[HTML][HTML] Synergistic effect of arginine and Lactobacillus plantarum against potassium dichromate induced-acute liver and kidney injury in rats: Role of iNOS and TLR4 …

AA Sedik, A Hassan, A Salama - Iranian Journal of Basic Medical …, 2023 - ncbi.nlm.nih.gov
Objective (s): Our study was conducted to evaluate the synergistic effect of arginine (ARG)
and Lactobacillus plantarum against potassium dichromate (K2Cr2O7) induced-acute …

Immunoregulatory role of hesperidin against ovalbumin (OVA)-induced bronchial asthma and depression in rats

A Salama, MSO Gouida, NN Yassen… - … schmiedeberg's Archives of …, 2024 - Springer
Links between bronchial asthma and depression have recently become a great subject of
interest. The present study was carried out to assess the protective role of hesperidin against …

Attenuation of sodium fluoride-induced hepatic injury by Lactobacillus casei through inhibition of NF-κβ signalling pathway with decreased expression of caspase-3 in …

AA Sedik, SA Hassan - Egyptian Journal of Chemistry, 2023 - journals.ekb.eg
Lactic acid bacteria play an important role in the human and animal defense against liver
damage. However, the potential mechanism of Lactobacillus casei (L. casei) on hepatic …

Neuromodulatory role of L-arginine: Nitric oxide precursor against thioacetamide-induced-hepatic encephalopathy in rats via downregulation of NF-κB-mediated …

AA Sedik, A Hassan, DO Saleh - Environmental Science and Pollution …, 2023 - Springer
The aim of the present study was to investigate the impact of arginine (ARG), a nitric oxide
(NO) precursor, on thioacetamide (TAA)-induced hepatic encephalopathy (HE) in rats by …

Establishment of acute liver failure model in Tibetan miniature pig and verified by dual plasma molecular adsorption system

Y Wang, C Zhou, Y Fu, L Zhang, S Liu… - … Journal of Artificial …, 2023 - journals.sagepub.com
Background: Acute liver failure (ALF) is a severe liver disease with high morbidity and
mortality rates. Animal models are important for research on ALF. This study aimed to …