Historically, benign prostatic hyperplasia (BPH) has been a major focus of urologic practice
and surgery. However, a simplistic causal relationship among prostatic enlargement …

Purpose Interstitial cystitis/painful bladder syndrome (IC/PBS) is a chronic pain syndrome
and a chronic inflammatory condition prevalent in women that leads to urgency, sleep …

Purinergic signalling is involved in a number of physiological and pathophysiological
activities in the lower urinary tract. In the bladder of laboratory animals there is …

The mechanism of visceral pain is still less understood compared with that of somatic pain.
This is primarily due to the diverse nature of visceral pain compounded by multiple factors …

This review deals with individual components regulating the neural control of the urinary
bladder. This article will focus on factors and processes involved in the two modes of …

A clinical guideline and algorism for interstitial cystitis and hypersensitive bladder syndrome
has been developed by a group of East Asian urologists as a revised form of the Japanese …

Treating pain by inhibiting ATP activation of P2X3-containing receptors heralds an exciting
new approach to pain management, and Afferent's program marks the vanguard in a new …

Purpose Intravesical onabotulinumtoxinA (BoNT‐A) injection is a beneficial treatment for
interstitial cystitis/bladder pain syndrome (IC/BPS), yet its therapeutic efficacy remains to be …

What's known on the subject? and What does the study add? Nearly 90% of patients with
interstitial cystitis/bladder pain syndrome (IC/BPS) report sensitivities to a wide variety of …

Background: Chronic pelvic pain (CPP) is a complex pain syndrome. Since its pathogenesis
is still poorly understood and structural alterations in pain related brain regions may be …