[HTML][HTML] In vivo methods and applications of xenon-129 magnetic resonance

H Marshall, NJ Stewart, HF Chan, M Rao… - Progress in Nuclear …, 2021 - Elsevier
Hyperpolarised gas lung MRI using xenon-129 can provide detailed 3D images of the
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …

Hyperpolarized Xe NMR signal advancement by metal-organic framework entrapment in aqueous solution

Q Zeng, B Bie, Q Guo, Y Yuan, Q Han… - Proceedings of the …, 2020 - National Acad Sciences
We report hyperpolarized Xe signal advancement by metal-organic framework (MOF)
entrapment (Hyper-SAME) in aqueous solution. The 129Xe NMR signal is drastically …

[HTML][HTML] Dynamic chest X-ray using a flat-panel detector system: technique and applications

A Hata, Y Yamada, R Tanaka, M Nishino… - Korean journal of …, 2021 - ncbi.nlm.nih.gov
Dynamic X-ray (DXR) is a functional imaging technique that uses sequential images
obtained by a flat-panel detector (FPD). This article aims to describe the mechanism of DXR …

[HTML][HTML] Accelerate gas diffusion-weighted MRI for lung morphometry with deep learning

C Duan, H Deng, S Xiao, J Xie, H Li, X Zhao, D Han… - European …, 2022 - Springer
Objectives Multiple b-value gas diffusion-weighted MRI (DW-MRI) enables non-invasive and
quantitative assessment of lung morphometry, but its long acquisition time is not well …

Protocols for multi‐site trials using hyperpolarized 129Xe MRI for imaging of ventilation, alveolar‐airspace size, and gas exchange: A position paper from the 129Xe …

PJ Niedbalski, CS Hall, M Castro… - Magnetic resonance …, 2021 - Wiley Online Library
Hyperpolarized (HP) 129Xe MRI uniquely images pulmonary ventilation, gas exchange, and
terminal airway morphology rapidly and safely, providing novel information not possible …

Seven pillars of small airways disease in asthma and COPD: supporting opportunities for novel therapies

OS Usmani, MLK Han, DA Kaminsky, J Hogg… - Chest, 2021 - Elsevier
Identification of pathologic changes in early and mild obstructive lung disease has shown
the importance of the small airways and their contribution to symptoms. Indeed, significant …

Pulmonary functional MRI: Detecting the structure–function pathologies that drive asthma symptoms and quality of life

HK Kooner, MJ McIntosh, V Desaigoudar… - …, 2022 - Wiley Online Library
Pulmonary functional MRI (PfMRI) using inhaled hyperpolarized, radiation‐free gases (such
as 3He and 129Xe) provides a way to directly visualize inhaled gas distribution and …

[HTML][HTML] PhysVENeT: a physiologically-informed deep learning-based framework for the synthesis of 3D hyperpolarized gas MRI ventilation

JR Astley, AM Biancardi, H Marshall, LJ Smith… - Scientific Reports, 2023 - nature.com
Functional lung imaging modalities such as hyperpolarized gas MRI ventilation enable
visualization and quantification of regional lung ventilation; however, these techniques …

Hyperpolarized 129Xe MRI, 99mTc scintigraphy, and SPECT in lung ventilation imaging: a quantitative comparison

JD Peiffer, T Altes, IC Ruset, FW Hersman… - Academic …, 2024 - Elsevier
Rationale and Objectives The current clinical standard for functional imaging of patients with
lung ailments is nuclear medicine scintigraphy and Single Photon Emission Computed …

[HTML][HTML] Dynamic chest radiography: clinical validation of ventilation and perfusion metrics derived from changes in radiographic lung density compared to nuclear …

R Tanaka, I Matsumoto, M Tamura… - … Imaging in Medicine …, 2021 - ncbi.nlm.nih.gov
Background Dynamic chest radiography (DCR) is a type of non-contrast-enhanced
functional lung imaging with a dynamic flat-panel detector (FPD). This study aimed to assess …