Estradiol secreted by growing ovarian follicle (s) has been considered classically to be the
neural trigger for the preovulatory surge of gonadotropins. The observation that the estradiol …

The preovulatory gonadotropin surge is induced by progesterone in the cycling female rat or
in the ovariectomized estrogen-treated female rat after adequate estrogen-priming activity is …

Objective: To evaluate the effects of short-course administration of dexamethasone (DEX)
combined with clomiphene citrate (CC) in CC-resistant patients with polycystic ovary …

Progesterone and its metabolites have a variety of diverse effects in the brain, uterus,
smooth muscle, sperm and the oocyte. The effects include changes in electrophysiological …

This career retrospective describes how the initial work on the mechanism of hormone
action provided the tools for the study of hirsutism, virilism, and polycystic ovarian disease …

Objective To evaluate the effect on ovulation of a 10-day course of dexamethasone (DEX)
initiated concurrently with a 5-day course of clomiphene citrate (CC) in CC-resistant patients …

Galanin has been shown to be an important neuropeptide associated with the preovulatory
surge of gonadotropins. Since the preovulatory surge of gonadotropins is induced by the …

There is considerable evidence that although estradiol may trigger the preovulatory surge of
gonadotropins, progesterone is required for its full magnitude and duration and that …

Objective Polycystic ovary syndrome (PCOS) is an endocrine gynecological disease
affecting many women of reproductive age. Clomiphene is the first-line treatment for PCOS …

In a previous study we reported that in vivo estrogen-priming alone, without subsequent
progester-one-treatment, was sufficient to maximize NPY potentiation of gonadotropin …