Radiomic analysis offers a powerful tool for the extraction of clinically relevant information
from radiologic imaging. Radiomics can be used to predict patient outcome through …

Tumor targeting by nanomedicine-based therapeutics has emerged as a promising
approach to overcome the lack of specificity of conventional chemotherapeutic agents and to …

The microenvironment characteristics of solid tumors, renowned as barriers that harshly
impeded many drug-delivery approaches, were precisely studied, investigated, categorized …

Cancer is a disease which frequently has a poor prognosis. Although multiple therapeutic
strategies have been developed for various cancers, including chemotherapy, radiotherapy …

The enhanced permeability and retention (EPR) of nanoparticles in tumors has long stood
as one of the fundamental principles of cancer drug delivery, holding the promise of safe …

Recent high-profile reports have reignited an interest in acetate metabolism in cancer. Acetyl-
CoA synthetases that catalyse the conversion of acetate to acetyl-CoA have now been …

Resistance of human tumors to anticancer drugs is most often ascribed to gene mutations,
gene amplification, or epigenetic changes that influence the uptake, metabolism, or export of …

Due to imbalances between vascularity and cellular growth patterns, the tumour
microenvironment harbours multiple metabolic stressors including hypoxia and acidosis …

The microenvironmental physiology of tumors is uniquely different from that of normal
tissues. It is characterized, inter alia, by O2 depletion (hypoxia, anoxia), glucose and energy …

Highlights•Nanocarriers with the ability to target tumors are being increasingly explored.•
Nanomedicine aid in maintaining a balance between efficacy and toxicity.•Recent advances …